Chlorhexidine, Dihydrochloride is an anti-microbial agent that acts as an inhibitor of MMP-2 and MMP-9 metalloproteinases. However, MMP-2 is more sensitive to chlorhexidine than MMP-9. Chlorhexidine dihydrochloride inhibits the collagenase activity of MMP-8 released by PMA-triggered polymorphonuclear leukocytes (PMNs) in a dose-dependent manner. Chlorhexidine dihydrochloride may possibly act through a cation-chelating mechanism.
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See how others have used Chlorhexidine, Dihydrochloride (CAS 3697-42-5). Click on the entry to view the PubMed entry .
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