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Chlorhexidine diacetate salt (CAS 56-95-1)

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Alternate Names:
Chlorhexidine acetate
Application:
Chlorhexidine diacetate salt is a cationic broad-spectrum antimicrobial agent
CAS Number:
56-95-1
Molecular Weight:
625.55
Molecular Formula:
C22H30Cl2N102C2H4O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Chlorhexidine diacetate salt functions as a broad-spectrum antimicrobial agent. It acts by disrupting the cell membrane of microorganisms, leading to leakage of cellular contents and ultimately causing cell death. Chlorhexidine Diacetate Salt′s mechanism of action involves binding to the negatively charged components of the bacterial cell wall, leading to disruption of the cell membrane integrity. This disruption results in the loss of intracellular components and eventual cell lysis. Chlorhexidine diacetate salt may have a residual antimicrobial effect, providing prolonged protection against microbial contamination. Its mechanism of action may be effective for controlling microbial growth in various experimental applications.


Chlorhexidine diacetate salt (CAS 56-95-1) References

  1. In vitro antibacterial effect of chlorhexidine added to glass-ionomer cements.  |  Ribeiro, J. and Ericson, D. 1991. Scand J Dent Res. 99: 533-40. PMID: 1763290
  2. Characterization of chlorhexidine-releasing, fast-setting, brushite bone cements.  |  Young, AM., et al. 2008. Acta Biomater. 4: 1081-8. PMID: 18313374
  3. Controlled release of chlorhexidine from amorphous microporous silica.  |  Verraedt, E., et al. 2010. J Control Release. 142: 47-52. PMID: 19804804
  4. Cytotoxicity of set polymer nanocomposite resin root-end filling materials.  |  Modareszadeh, MR., et al. 2011. Int Endod J. 44: 154-61. PMID: 21083578
  5. Strength characteristics and marginal sealing ability of chlorhexidine-modified glass ionomer cement: an in vitro study.  |  Ahluwalia, P., et al. 2012. J Indian Soc Pedod Prev Dent. 30: 41-6. PMID: 22565516
  6. Resins-based denture soft lining materials modified by chlorhexidine salt incorporation: an in vitro analysis of antifungal activity, drug release and hardness.  |  Bertolini, MM., et al. 2014. Dent Mater. 30: 793-8. PMID: 24933229
  7. Evaluation of the Microleakage of Chlorhexidine-Modified Glass Ionomer Cement: An in vivo Study.  |  Mathew, SM., et al. 2013. Int J Clin Pediatr Dent. 6: 7-11. PMID: 25206179
  8. Effect of monomer blend and chlorhexidine-adding on physical, mechanical and biological properties of experimental infiltrants.  |  Inagaki, LT., et al. 2016. Dent Mater. 32: e307-e313. PMID: 28327302
  9. Self-cured resin modified by quaternary ammonium methacrylates and chlorhexidine: Cytotoxicity, antimicrobial, physical, and mechanical properties.  |  Campos, KPL., et al. 2020. Dent Mater. 36: 68-75. PMID: 31735423
  10. Evaluation of the physical and antifungal effects of chlorhexidine diacetate incorporated into polymethyl methacrylate.  |  Maluf, CV., et al. 2020. J Appl Oral Sci. 28: e20190039. PMID: 31939520
  11. In vitro evaluation of physicochemical properties of soft lining resins after incorporation of chlorhexidine.  |  Maluf, CV., et al. 2020. J Prosthet Dent. 124: 615.e1-615.e7. PMID: 32540125
  12. Determination of chlorhexidine in saliva using high-performance liquid chromatography.  |  Pesonen, T., et al. 1995. J Chromatogr B Biomed Appl. 665: 222-5. PMID: 7795796

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Chlorhexidine diacetate salt, 1 g

sc-252569B
1 g
$38.00

Chlorhexidine diacetate salt, 5 g

sc-252569C
5 g
$78.00

Chlorhexidine diacetate salt, 25 g

sc-252569
25 g
$171.00

Chlorhexidine diacetate salt, 100 g

sc-252569A
100 g
$520.00