Date published: 2025-10-14

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Chlordecone (CAS 143-50-0)

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Alternate Names:
Kepone; chlordecone
Application:
Chlordecone is an organochlorine compound
CAS Number:
143-50-0
Molecular Weight:
490.64
Molecular Formula:
C10Cl10O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Chlordecone is a synthetic chlorinated organic compound, notable for its use as a pesticide. This compound operates through a specific mechanism of action, primarily affecting the nervous system of targeted pest species by disrupting the normal function of neurotransmitters, which are critical for nerve impulse transmission. In research applications, chlordecone has been extensively studied for its environmental persistence and bioaccumulation potential, leading to significant interest in its impact on ecosystems and wildlife. Studies have focused on understanding its degradation pathways, environmental distribution, and the mechanisms through which it exerts toxic effects on non-target organisms. Its role in research extends to serving as a model compound for studying the long-term environmental and ecological consequences of persistent organic pollutants (POPs), which remain in ecosystems for extended periods and pose risks to environmental health and biodiversity.


Chlordecone (CAS 143-50-0) References

  1. Organochlorine (chlordecone) uptake by root vegetables.  |  Florence, C., et al. 2015. Chemosphere. 118: 96-102. PMID: 25043888
  2. Chlordecone exposure and adverse effects in French West Indies populations.  |  Multigner, L., et al. 2016. Environ Sci Pollut Res Int. 23: 3-8. PMID: 25940496
  3. Chlordecone consumption estimated by sewage epidemiology approach for health policy assessment.  |  Devault, DA., et al. 2018. Environ Sci Pollut Res Int. 25: 29633-29642. PMID: 30144006
  4. Chlordecone potentiates auto-immune hepatitis and promotes brain entry of MHV3 during viral hepatitis in mouse models.  |  Tabet, E., et al. 2018. Toxicol Lett. 299: 129-136. PMID: 30287270
  5. Environmental fate of chlordecone in coastal habitats: recent studies conducted in Guadeloupe and Martinique (Lesser Antilles).  |  Dromard, CR., et al. 2022. Environ Sci Pollut Res Int. 29: 51-60. PMID: 30827027
  6. Natural Chlordecone Degradation Revealed by Numerous Transformation Products Characterized in Key French West Indies Environmental Compartments.  |  Chevallier, ML., et al. 2019. Environ Sci Technol. 53: 6133-6143. PMID: 31082212
  7. Linear toxicokinetic of chlordecone in ewe's serum.  |  Saint-Hilaire, M., et al. 2020. Environ Sci Pollut Res Int. 27: 40963-40970. PMID: 31256406
  8. Chlordecone exposure and risk of congenital anomalies: the Timoun Mother-Child Cohort Study in Guadeloupe (French West Indies).  |  Rouget, F., et al. 2020. Environ Sci Pollut Res Int. 27: 40992-40998. PMID: 31376129
  9. Chlordecone and organochlorine compound levels in the French West Indies population in 2013-2014.  |  Dereumeaux, C., et al. 2020. Environ Sci Pollut Res Int. 27: 41033-41045. PMID: 31884530
  10. Affinity of chlordecone and chlordecol for human serum lipoproteins.  |  Delannoy, M., et al. 2020. Environ Toxicol Pharmacol. 80: 103486. PMID: 32891758
  11. Arsenic and chlordecone contamination and decontamination toxicokinetics in Sargassum sp.  |  Devault, DA., et al. 2022. Environ Sci Pollut Res Int. 29: 6-16. PMID: 33415641
  12. Evidence of Chlordecone Resurrection by Glyphosate in French West Indies.  |  Sabatier, P., et al. 2021. Environ Sci Technol. 55: 2296-2306. PMID: 33507080
  13. Characterization and quantification of chlordecone elimination in ewes.  |  Saint-Hilaire, M., et al. 2021. Environ Toxicol Pharmacol. 87: 103698. PMID: 34224866
  14. Chlordecone: development of a physiologically based pharmacokinetic tool to support human health risks assessments.  |  Emond, C. and Multigner, L. 2022. Arch Toxicol. 96: 1009-1019. PMID: 35122515
  15. Chlordecone-contaminated epilithic biofilms show increased adsorption capacities.  |  Hubas, C., et al. 2022. Sci Total Environ. 825: 153942. PMID: 35189234

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Chlordecone, 100 mg

sc-394278
100 mg
$165.00

Chlordecone, 1 g

sc-394278A
1 g
$1430.00

Chlordecone, 7 g

sc-394278B
7 g
$8160.00

Chlordecone, 10 g

sc-394278C
10 g
$11220.00