Chlorbufam (CAS 1967-16-4)

Chlorbufam, a synthetic herbicide, finds application in agriculture and horticulture for weed control, targeting both grasses and broadleaves. Belonging to the sulfonylurea herbicide class, it has been utilized since the late 1960s. Operating as a non-selective herbicide, Chlorbufam exhibits efficacy against a wide spectrum of weed species, without distinguishing between weeds and other plants. However, caution must be exercised as it poses toxicity risks to humans, animals, and the environment if not appropriately employed. Extensive scientific research has focused on Chlorbufam, exploring various applications. It has been instrumental in investigating the impact of herbicides on plant growth, development, and soil microbial communities. Additionally, Chlorbufam has facilitated studies on herbicide effects on aquatic ecosystems and human health. Its mode of action involves the inhibition of acetolactate synthase (ALS), an enzyme for the biosynthesis of the amino acids valine and isoleucine. By hindering ALS, Chlorbufam disrupts the production of these vital amino acids, leading to growth inhibition in the plant. This mechanism aligns with other sulfonylurea herbicides like metsulfuron-methyl and flazasulfuron.