Molecular structure of Chenodeoxycholic Acid, Sodium Salt, CAS Number: 2646-38-0
Chenodeoxycholic Acid, Sodium Salt (CAS 2646-38-0)
See product citations (2)
Alternate Names:
3α,7α-Dihydroxy-5β-cholanic acid; Chenodesoxycholic acid; Chenodiol
Application:
Chenodeoxycholic Acid, Sodium Salt is a bile acid used in rat hepatocyte studies
CAS Number:
2646-38-0
Molecular Weight:
414.60
Molecular Formula:
C24H39O4•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Chenodeoxycholic Acid, Sodium Salt (CDCA) is a bile acid that may act to increase intracellular Ca2+ in isolated rat hepatocyte couplets. It induces a permeability transition in freshly isolated rat liver mitochondria. Chenodeoxycholic Acid, Sodium Salt acts as a detergent, solubilizing lipids and aiding in the digestion and absorption of fats, vitamins, and other nutrients. It also acts as a bile acid transporter, transporting bile acids from the intestine to the liver. It may act to reduce inflammation, reduce oxidative stress, and improve metabolic health.
Chenodeoxycholic Acid, Sodium Salt (CAS 2646-38-0) References
- Absorption of montelukast is transporter mediated: a common variant of OATP2B1 is associated with reduced plasma concentrations and poor response. | Mougey, EB., et al. 2009. Pharmacogenet Genomics. 19: 129-38. PMID: 19151602
- Effects of chenodeoxycholic acid on the secretion of gut peptides and fibroblast growth factors in healthy humans. | Meyer-Gerspach, AC., et al. 2013. J Clin Endocrinol Metab. 98: 3351-8. PMID: 23783097
- Effects of 5 beta-chol-3-en-24-oic acid, and lithocholic acid and its sulfates on prostaglandin E2 output in perfusion of the rat colon. | Hikasa, Y., et al. 1989. Gastroenterol Jpn. 24: 16-21. PMID: 2707548
- The effect of bile acids on the growth and global gene expression profiles in Akkermansia muciniphila. | Hagi, T., et al. 2020. Appl Microbiol Biotechnol. 104: 10641-10653. PMID: 33159542
- Induction of the maternal pheromone by cholic acid in the virgin rat. | Kilpatrick, SJ., et al. 1980. Physiol Behav. 25: 31-4. PMID: 7413815
Activator of:
Uroguanylin.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Chenodeoxycholic Acid, Sodium Salt, 5 g | sc-280637 | 5 g | $67.00 | |||
Chenodeoxycholic Acid, Sodium Salt, 25 g | sc-280637A | 25 g | $151.00 | |||
Chenodeoxycholic Acid, Sodium Salt, 100 g | sc-280637B | 100 g | $426.00 | |||
Chenodeoxycholic Acid, Sodium Salt, 250 g | sc-280637C | 250 g | $988.00 |