Molecular structure of Cheirolin, CAS Number: 505-34-0
Cheirolin (CAS 505-34-0)
Alternate Names:
1-Isothiocyanato-3-(methylsulfonyl)-propane
Application:
Cheirolin is a phase II detoxification enzyme activator
CAS Number:
505-34-0
Molecular Weight:
179.26
Molecular Formula:
C5H9NO2S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Cheirolin is a glucosinolate from plants of the Brassicaceae family which has shown to be a potent inducer of phase II detoxification enzymes.
Cheirolin (CAS 505-34-0) References
- Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: comparison of allyl isothiocyanate with sulforaphane and related compounds. | Munday, R. and Munday, CM. 2004. J Agric Food Chem. 52: 1867-71. PMID: 15053522
- Synthesis and Nrf2-inducing activity of the isothiocyanates iberverin, iberin and cheirolin. | Ernst, IM., et al. 2013. Pharmacol Res. 70: 155-62. PMID: 23403058
- The Role of Lysosome-associated Membrane Protein 2 in Prostate Cancer Chemopreventive Mechanisms of Sulforaphane. | Hahm, ER., et al. 2020. Cancer Prev Res (Phila). 13: 661-672. PMID: 32434809
- Induction of the Stringent Response Underlies the Antimicrobial Action of Aliphatic Isothiocyanates. | Nowicki, D., et al. 2020. Front Microbiol. 11: 591802. PMID: 33584562
- Effect of bioactive compounds released from Brassicaceae defatted seed meals on bacterial load in pig manure. | Ugolini, L., et al. 2021. Environ Sci Pollut Res Int. 28: 62353-62367. PMID: 34191264
- Anti-Inflammatory Activity and Quality Control of Erysimum cheiri (L.) Crantz. | Mosleh, G., et al. 2021. Biomed Res Int. 2021: 5526644. PMID: 34212031
- Activation of MEK1/2/Nrf-2 Signaling Pathway by Epstein-Barr Virus-Latent Membrane Protein 1 Enhances Autophagy and Cisplatin Resistance in T-Cell Lymphoma. | Jia, X., et al. 2021. Anal Cell Pathol (Amst). 2021: 6668947. PMID: 34239803
- Sulforaphane and Its Bifunctional Analogs: Synthesis and Biological Activity. | Janczewski, Ł. 2022. Molecules. 27: PMID: 35268851
- Assessment of Methodological Pipelines for the Determination of Isothiocyanates Derived from Natural Sources. | Kyriakou, S., et al. 2022. Antioxidants (Basel). 11: PMID: 35453327
- Sulforaphane and bladder cancer: a potential novel antitumor compound. | Zuo, M., et al. 2023. Front Pharmacol. 14: 1254236. PMID: 37781700
Activator of:
Enzyme.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cheirolin, 25 mg | sc-205627 | 25 mg | $214.00 | |||
Cheirolin, 50 mg | sc-205627A | 50 mg | $357.00 | |||
Cheirolin, 100 mg | sc-205627B | 100 mg | $645.00 | |||
Cheirolin, 500 mg | sc-205627C | 500 mg | $2100.00 |