Molecular structure of CHAPSO, CAS Number: 82473-24-3
CHAPSO (CAS 82473-24-3)
Alternate Names:
3-([3-Cholamidopropyl]dimethylammonio)-2-hydroxy-1-propanesulfonate
Application:
CHAPSO is a unique detergent with high CMC
CAS Number:
82473-24-3
Purity:
95%
Molecular Weight:
630.88
Molecular Formula:
C32H58N2O8S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
CHAPSO is a unique detergent with high CMC that solubilizes membrane-bound proteins in their native state. CHAPSO is capable of solubilizing opiate receptor to a state exhibiting reversible binding of opiates. Has higher solubility than CHAPS because of its more polar head group.
CHAPSO (CAS 82473-24-3) References
- Improved low pH bicelle system for orienting macromolecules over a wide temperature range. | Cavagnero, S., et al. 1999. J Biomol NMR. 13: 387-91. PMID: 10353198
- Alzheimer amyloid precursor aspartyl proteinase activity in CHAPSO homogenates of Spodoptera frugiperda cells. | Carter, TL., et al. 2004. Alzheimer Dis Assoc Disord. 18: 261-3. PMID: 15592142
- Active gamma-secretase is localized to detergent-resistant membranes in human brain. | Hur, JY., et al. 2008. FEBS J. 275: 1174-87. PMID: 18266764
- Quantum yield of CHAPSO-solubilized rhodopsin and 3-hydroxy retinal containing bovine opsin. | Gärtner, W., et al. 1991. Photochem Photobiol. 54: 1047-55. PMID: 1837929
- Interactions of hemin with model erythrocyte membranes. | Qutub, Y., et al. 2010. J Phys Chem B. 114: 4529-35. PMID: 20235510
- Magnetically orientable phospholipid bilayers containing small amounts of a bile salt analogue, CHAPSO. | Sanders, CR. and Prestegard, JH. 1990. Biophys J. 58: 447-60. PMID: 2207249
- Morphological characterization of DMPC/CHAPSO bicellar mixtures: a combined SANS and NMR study. | Li, M., et al. 2013. Langmuir. 29: 15943-57. PMID: 24059815
- Detergent induces the formation of IgG aggregates: a multi-methodological approach. | Amani, S., et al. 2014. Spectrochim Acta A Mol Biomol Spectrosc. 120: 151-60. PMID: 24184618
- Automated analysis of calorimetric demicellization titrations. | Textor, M. and Keller, S. 2015. Anal Biochem. 485: 119-21. PMID: 26079704
- Impact of Detergents on Membrane Protein Complex Isolation. | Lee, YC., et al. 2018. J Proteome Res. 17: 348-358. PMID: 29110486
- Eliminating effects of particle adsorption to the air/water interface in single-particle cryo-electron microscopy: Bacterial RNA polymerase and CHAPSO. | Chen, J., et al. 2019. J Struct Biol X. 1: PMID: 32285040
- Solid state 13C NMR of unlabeled phosphatidylcholine bilayers: spectral assignments and measurement of carbon-phosphorus dipolar couplings and 13C chemical shift anisotropies. | Sanders, CR. 1993. Biophys J. 64: 171-81. PMID: 8431541
- Liposome solubilization and membrane protein reconstitution using Chaps and Chapso. | Cladera, J., et al. 1997. Eur J Biochem. 243: 798-804. PMID: 9057848
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CHAPSO, 500 mg | sc-280635 | 500 mg | $75.00 | |||
CHAPSO, 1 g | sc-280635A | 1 g | $114.00 | |||
CHAPSO, 5 g | sc-280635B | 5 g | $208.00 |