Molecular structure of Chalcone, CAS Number: 614-47-1
Chalcone (CAS 614-47-1)
See product citations (6)
Alternate Names:
trans-Chalcone; Benzylideneacetophenone; 2-(Benzylidene)acetophenone
Application:
Chalcone is an open chain flavonoid that may prevent lung and forestomach cancer
CAS Number:
614-47-1
Purity:
≥97%
Molecular Weight:
208.26
Molecular Formula:
C15H12O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Chalcone is a precursor in the synthesis of various flavonoids and isoflavonoids. It acts as a key intermediate in the biosynthesis of these compounds. Chalcone exerts its mechanism of action by undergoing various chemical reactions, such as cyclization and oxidation, leading to the production of structurally diverse compounds with potential biological activities. Its molecular structure allows it to participate in condensation reactions with different types of aromatic compounds. Its mechanism of action at the molecular level involves interactions with specific enzymes and substrates, leading to the formation of complex chemical structures with potential biological activities.
Chalcone (CAS 614-47-1) References
- Synthesis and biological evaluation of chalcone derivatives (mini review). | Bukhari, SN., et al. 2012. Mini Rev Med Chem. 12: 1394-403. PMID: 22876958
- Chalcone: A Privileged Structure in Medicinal Chemistry. | Zhuang, C., et al. 2017. Chem Rev. 117: 7762-7810. PMID: 28488435
- Chalcone Derivatives: Promising Starting Points for Drug Design. | Gomes, MN., et al. 2017. Molecules. 22: PMID: 28757583
- A comprehensive review of chalcone derivatives as antileishmanial agents. | de Mello, MVP., et al. 2018. Eur J Med Chem. 150: 920-929. PMID: 29602038
- Chalcone derivatives as non-canonical ligands of TRPV1. | Benso, B., et al. 2019. Int J Biochem Cell Biol. 112: 18-23. PMID: 31026506
- Chalcone hybrids as privileged scaffolds in antimalarial drug discovery: A key review. | Qin, HL., et al. 2020. Eur J Med Chem. 193: 112215. PMID: 32179331
- Chalcone hybrids as potential anticancer agents: Current development, mechanism of action, and structure-activity relationship. | Gao, F., et al. 2020. Med Res Rev. 40: 2049-2084. PMID: 32525247
- A chalcone inhibits the growth and metastasis of KYSE-4 esophageal cancer cells. | Chen, J., et al. 2020. J Int Med Res. 48: 300060520928831. PMID: 32588681
- Development of chalcone-based derivatives for sensing applications. | Gupta, A., et al. 2020. Anal Methods. 12: 5022-5045. PMID: 33103673
- Chalcone T4, a novel chalconic compound, inhibits inflammatory bone resorption in vivo and suppresses osteoclastogenesis in vitro. | Fernandes, NAR., et al. 2021. J Periodontal Res. 56: 569-578. PMID: 33641160
- Chalcone Scaffolds, Bioprecursors of Flavonoids: Chemistry, Bioactivities, and Pharmacokinetics. | Rudrapal, M., et al. 2021. Molecules. 26: PMID: 34885754
- Oncopreventive and Oncotherapeutic Potential of Licorice Chalcone Compounds: Molecular Insights. | Wang, Y., et al. 2023. Mini Rev Med Chem. 23: 662-699. PMID: 36043713
- Recent advances in the antioxidant activity and mechanisms of chalcone derivatives: a computational review. | Mittal, A., et al. 2022. Free Radic Res. 56: 378-397. PMID: 36063087
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Chalcone, 25 g | sc-204681 | 25 g | $49.00 | |||
Chalcone, 100 g | sc-204681A | 100 g | $88.00 |