Molecular structure of CH 55, CAS Number: 110368-33-7
CH 55 (CAS 110368-33-7)
Alternate Names:
3,5-Di-tert-butylchalcone
Application:
CH 55 is a synthetic retinoid with high affinity at RAR-α and β
CAS Number:
110368-33-7
Molecular Weight:
364.47
Molecular Formula:
C24H28O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Highly potent, synthetic retinoid that has high affinity for RAR-α and RAR-β receptors and low affinity for cellular retinoic acid binding protein (CRABP). Induces differentiation of embryonic carcinoma F9 and melanoma S91 cells (EC50 values are 0.26 and 0.5 nM respectively) and inhibits the induction of ornithine decarboxylase activity in 3T6 fibroblasts (EC50 = 1 nM). Inhibits rabbit tracheal epithelial cell differentiation by inhibiting transglutaminase and increasing cholesterol sulfate (EC50 values are 0.02 and 0.03 nM respectively).
CH 55 (CAS 110368-33-7) References
- Chalcones, myo-inositol and other novel inhibitors of pulmonary carcinogenesis. | Wattenberg, L. 1995. J Cell Biochem Suppl. 22: 162-8. PMID: 8538194
Inhibitor of:
RARα, RARα2, and TIG2.Activator of:
RAR alpha, RAR beta, and RARα1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CH 55, 10 mg | sc-203884 | 10 mg | $138.00 | |||
CH 55, 50 mg | sc-203884A | 50 mg | $587.00 |