Molecular structure of CGP-60474, CAS Number: 164658-13-3
CGP-60474 (CAS 164658-13-3)
Alternate Names:
CGP60474 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol CGP 60474 1-Propanol, 3-[[4-[2-[(3-chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-
CAS Number:
164658-13-3
Molecular Weight:
355.80
Molecular Formula:
C18H18ClN5O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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CGP-60474 (CAS 164658-13-3) References
- Novel and efficient access to phenylamino-pyrimidine type protein kinase C inhibitors utilizing a Negishi cross-coupling strategy. | Stanetty, P., et al. 2005. J Org Chem. 70: 5215-20. PMID: 15960526
- LINCS L1000 dataset-based repositioning of CGP-60474 as a highly potent anti-endotoxemic agent. | Han, HW., et al. 2018. Sci Rep. 8: 14969. PMID: 30297806
- Drug candidate identification based on gene expression of treated cells using tensor decomposition-based unsupervised feature extraction for large-scale data. | Taguchi, YH. 2019. BMC Bioinformatics. 19: 388. PMID: 30717646
- A new advanced in silico drug discovery method for novel coronavirus (SARS-CoV-2) with tensor decomposition-based unsupervised feature extraction. | Taguchi, YH. and Turki, T. 2020. PLoS One. 15: e0238907. PMID: 32915876
- Prediction of repurposed drugs for treating lung injury in COVID-19. | He, B. and Garmire, L. 2020. F1000Res. 9: 609. PMID: 32934806
- Comprehensive Analysis Identifies Potential Ferroptosis-Associated mRNA Therapeutic Targets in Ovarian Cancer. | Zhang, J., et al. 2021. Front Med (Lausanne). 8: 644053. PMID: 33748162
- Drug repositioning based on gene expression data for human HER2-positive breast cancer. | Khanjani, F., et al. 2021. Arch Biochem Biophys. 712: 109043. PMID: 34597657
- Metabolomic analysis of vascular cognitive impairment due to hepatocellular carcinoma. | Zhu, D., et al. 2022. Front Neurol. 13: 1109019. PMID: 37008043
- Identification of memory B-cell-associated miRNA signature to establish a prognostic model in gastric adenocarcinoma. | Liu, R., et al. 2023. J Transl Med. 21: 648. PMID: 37735667
- Bioinformatics analysis identifies coagulation factor II receptor as a potential biomarker in stomach adenocarcinoma. | Wu, X., et al. 2024. Sci Rep. 14: 2468. PMID: 38291086
Inhibitor of:
CRY1, EDG-4, eIF1, IQGAP1, MELK, Mnk2, MYT1L, phospholamban, and TADA2B.Activator of:
Clb2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CGP-60474, 5 mg | sc-507525 | 5 mg | $165.00 |