Molecular structure of CGP 3466B maleate, CAS Number: 200189-97-5
CGP 3466B maleate (CAS 200189-97-5)
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Alternate Names:
CH 346 maleate; N-(Dibenz[b,f]oxepin-10-ylmethyl)-N -Methyl-N-(2-propynyl)amine maleate
Application:
CGP 3466B maleate is a glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor
CAS Number:
200189-97-5
Purity:
≥98%
Molecular Weight:
391.42
Molecular Formula:
C19H17NO•C4H4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
CGP 3466B maleate has been reported to be a GAPDH (glyceraldehyde-3-phosphate dehydrogenase) inhibitor. Studies show that this compound contains antiapoptotic properties. It also exhibits neuroprotective properties in vivo.
CGP 3466B maleate (CAS 200189-97-5) References
- Highly Expressed Genes in Rapidly Proliferating Tumor Cells as New Targets for Colorectal Cancer Treatment. | Bazzocco, S., et al. 2015. Clin Cancer Res. 21: 3695-704. PMID: 25944804
- Glycolysis regulates pollen tube polarity via Rho GTPase signaling. | Chen, W., et al. 2018. PLoS Genet. 14: e1007373. PMID: 29702701
- Host Proteins Identified in Extracellular Viral Particles as Targets for Broad-Spectrum Antiviral Inhibitors. | Gale, TV., et al. 2019. J Proteome Res. 18: 7-17. PMID: 30351952
- Reducing acetylated tau is neuroprotective in brain injury. | Shin, MK., et al. 2021. Cell. 184: 2715-2732.e23. PMID: 33852912
- Bioenergetics of pollen tube growth in Arabidopsis thaliana revealed by ratiometric genetically encoded biosensors. | Liu, J., et al. 2022. Nat Commun. 13: 7822. PMID: 36535933
- Therapeutic potential of blocking GAPDH nitrosylation with CGP3466b in experimental autoimmune encephalomyelitis. | Godfrey, WH., et al. 2022. Front Neurol. 13: 979659. PMID: 36761918
Inhibitor of:
GAPDH, and LASS1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CGP 3466B maleate, 10 mg | sc-361137 | 10 mg | $327.00 | |||
| US: Only available in the US | ||||||
CGP 3466B maleate, 50 mg | sc-361137A | 50 mg | $1301.00 | |||
| US: Only available in the US | ||||||