Molecular structure of CGP 12177 hydrochloride, CAS Number: 81047-99-6
CGP 12177 hydrochloride (CAS 81047-99-6)
Alternate Names:
4-[3-(tert-butylamino)-2-hydroxypropoxy]-1,3-dihydrobenzimidazol-2-one hydrochloride
Application:
CGP 12177 hydrochloride is a β1/β2-AR adrenoreceptor agonist
CAS Number:
81047-99-6
Molecular Weight:
315.8
Molecular Formula:
C14H22ClN3O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
CGP 12177 hydrochloride is a β1-AR and β2-AR adrenoreceptor antagonist. Also behaves non-conventionally as a β3-AR partial agonist.
CGP 12177 hydrochloride (CAS 81047-99-6) References
Staehelin et al (1983) CGP-12177. A hydrophilic beta-adrenergic receptor radioligand reveals high affinity binding of agonists to intact cells. J.Biol.Chem. 258 3496. Strosberg and Pietri-Rouxel (1996) Function and regulation of the b3-adrenoceptor. TiPS 17 373. Galitzky et al (1998) On the presence of a putative fourth b-adrenoceptor in human adipose tissue. TiPS 19 164. Preitner et al (1998) Metabolic response to various b-adrenoceptor agonists in b3-adrenoceptor knockout mice: evidence for a new b-adrenergic receptor in brown adipose tissue. Br.J.Pharmacol. 124 1684.Inhibitor of:
beta1-AR, and beta2-AR.Activator of:
beta3-AR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CGP 12177 hydrochloride, 10 mg | sc-203878 | 10 mg | $85.00 | |||
| US: Only available in the US | ||||||
CGP 12177 hydrochloride, 50 mg | sc-203878A | 50 mg | $275.00 | |||
| US: Only available in the US | ||||||