CFTR Inhibitor II, GlyH-101 (CAS 328541-79-3)
CFTR Inhibitor II, GlyH-101 is a cell-permeable glycinyl hydrazone compound that blocks CFTR.
References
1. Laverty, G. et al. 2012. Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. 161(1): 53-60. PMID: 21964154
> 15277574, 16317066, 21964154 1. Muanprasat, C. et al. 2004. J. Gen. Physiol. 124(2): 125-137. PMID: 15277574
2. Sonawane, N.D. et al. 2006. FASEB J. 20(1): 130-132. PMID: 16317066
3. Laverty, G. et al. 2012. Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. 161(1): 53-60. PMID: 21964154
Download SDS (MSDS)
SAMPLE Certificate of Analysis (COA)
CFTR Inhibitor II, GlyH-101 | CAS 328541-79-3 SAMPLE Certificate of AnalysisCertificate of Analysis
SAMPLE Certificate of Analysis (COA)
| Test | Specification | Results |
|---|---|---|
| Appearance | Yellow solid | |
| Purity | ≥ 97% |
CFTR Inhibitor II, GlyH-101 (CAS 328541-79-3) Product Citations
See how others have used CFTR Inhibitor II, GlyH-101 (CAS 328541-79-3). Click on the entry to view the PubMed entry .
PMID: 29351391 | The bile acids, deoxycholic acid and ursodeoxycholic acid, regulate colonic epithelial wound healing. | Mroz, MS. et al. 2018. Am. J. Physiol. Gastrointest. Liver Physiol. 314: G378-G387.
PMID: 28701694 | Defective CFTR leads to aberrant β-catenin activation and kidney fibrosis. | Zhang, JT. et al. 2017. Sci Rep. 7: 5233.
PMID: 28428011 | CFTR-dependent defect in alternatively-activated macrophages in cystic fibrosis. | Tarique, AA. et al. 2017. J. Cyst. Fibros. 16: 475-482.
PMID: 28455748 | CK2 is a key regulator of SLC4A2-mediated Cl-/HCO3- exchange in human airway epithelia. | Ibrahim, SH. et al. 2017. Pflugers Arch. 469: 1073-1091.
PMID: 27827428 | PGE2 is a direct and robust mediator of anion/fluid secretion by human intestinal epithelial cells. | Fujii, S. et al. 2016. Sci Rep. 6: 36795.
PMID: 25792563 | Calcium-sensing receptor stimulates Cl(-)- and SCFA-dependent but inhibits cAMP-dependent HCO3(-) secretion in colon. | Tang, L. et al. 2015. Am. J. Physiol. Gastrointest. Liver Physiol. 308: G874-83.
PMID: 32306956 | Negative chronotropic and inotropic effects of lubiprostone on iPS cell-derived cardiomyocytes via activation of CFTR. | BMC Complement Med Ther. 20: 118.