Molecular structure of cFMS Receptor Inhibitor III, CAS Number: 959861-21-3
cFMS Receptor Inhibitor III (CAS 959861-21-3)
Alternate Names:
4-(3,4-Dimethylanilino)-7-(4-(methylsulfonyl)phenyl)quinoline-3-carboxamide; CSF-1 Receptor Inhibitor III
Application:
cFMS Receptor Inhibitor III is a cell-permeable anilinoquinoline compound
CAS Number:
959861-21-3
Molecular Weight:
445.53
Molecular Formula:
C25H23N3O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
cFMS Receptor Inhibitor III is a cell-permeable anilinoquinoline compound that acts as a strong, active site-targeting inhibitor of MCSF receptor/cFMS. cFMS Receptor Inhibitor III is 100-fold more potent in inhibiting the cFMS-dependent growth of M-NSF-60 cells than the cFMS-independent growth of NSO cells.
cFMS Receptor Inhibitor III (CAS 959861-21-3) References
- Synthesis of novel anilinoquinolines as c-fms inhibitors. | Smalley, TL., et al. 2007. Bioorg Med Chem Lett. 17: 6257-60. PMID: 17870531
- New models of atherosclerosis and multi-drug therapeutic interventions. | Parton, A., et al. 2019. Bioinformatics. 35: 2449-2457. PMID: 30520978
- Long-term implant fibrosis prevention in rodents and non-human primates using crystallized drug formulations. | Farah, S., et al. 2019. Nat Mater. 18: 892-904. PMID: 31235902
Inhibitor of:
c-Fms-CSF-1R, and M-CSF.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cFMS Receptor Inhibitor III, 1 mg | sc-221416 | 1 mg | $178.00 |