Molecular structure of cFMS Receptor Inhibitor II, CAS Number: 959860-85-6
cFMS Receptor Inhibitor II (CAS 959860-85-6)
See product citations (2)
Alternate Names:
4-(3,4-Dimethylphenylamino)-7-(pyridin-4-yl)quinoline-3-carboxamide
Application:
cFMS Receptor Inhibitor II is a cell-permeable anilinoquinoline compound
CAS Number:
959860-85-6
Molecular Weight:
368.4
Molecular Formula:
C23H20N4O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
cFMS Receptor Inhibitor II, also known as CFMS-RI-II, represents a groundbreaking small-molecule inhibitor that specifically targets the c-FMS receptor tyrosine kinase. The mechanism of action of cFMS Receptor Inhibitor II involves its binding to the c-FMS receptor tyrosine kinase, leading to the inhibition of its activity. In vitro experiments have further revealed its ability to attenuate the proliferation and activation of both T-cells and B-cells. Additionally, cFMS Receptor Inhibitor II exhibits the capacity to diminish the generation of reactive oxygen species and nitric oxide, offering potential therapeutic benefits in oxidative stress-related conditions.
cFMS Receptor Inhibitor II (CAS 959860-85-6) References
- Synthesis of novel anilinoquinolines as c-fms inhibitors. | Smalley, TL., et al. 2007. Bioorg Med Chem Lett. 17: 6257-60. PMID: 17870531
Inhibitor of:
c-Fms-CSF-1R.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cFMS Receptor Inhibitor II, 500 µg | sc-221415 | 500 µg | $118.00 | |||
cFMS Receptor Inhibitor II, 1 mg | sc-221415A | 1 mg | $223.00 |