Cetraxate, Hydrochloride (CAS 27724-96-5)
QUICK LINKS
Cetraxate, Hydrochloride is a compound that functions as a potent and selective inhibitor of a specific enzyme. It acts by binding to the active site of the enzyme, preventing its normal substrate from binding and inhibiting its catalytic activity. This inhibition disrupts a key biochemical pathway, leading to downstream effects on cellular processes. The compound′s mechanism of action involves specific interactions with amino acid residues within the enzyme′s active site, leading to conformational changes that impair its function. This disruption at the molecular level has implications for the regulation of various cellular functions and signaling pathways. The compound′s ability to modulate the activity of this enzyme is useful for investigating the role of this pathway in cellular physiology.
Cetraxate, Hydrochloride (CAS 27724-96-5) References
- Enzymatic preparation of D-beta-acetylthioisobutyric acid and cetraxate hydrochloride using a stereo- and/or regioselective hydrolase, 3,4-dihydrocoumarin hydrolase from Acinetobacter calcoaceticus. | Honda, K., et al. 2002. Appl Microbiol Biotechnol. 60: 288-92. PMID: 12436309
- Influence of anti-ulcer drugs used in Japan on the result of (13)C-urea breath test for the diagnosis of Helicobacter pylori infection. | Murakami, K., et al. 2003. J Gastroenterol. 38: 937-41. PMID: 14614600
- Cetraxate raises levels of calcitonin gene-related peptide and substance P in human plasma. | Katagiri, F., et al. 2004. J Pharm Pharmacol. 56: 557-61. PMID: 15099451
- Comparison of the effects of cytoprotective drugs on human plasma adrenocorticotropic hormone and cortisol levels with continual stress exposure. | Katagiri, F., et al. 2005. Biol Pharm Bull. 28: 2146-8. PMID: 16272707
- [The effect of aldioxa on the formation of gastritis induced with sodium hydroxide]. | Ohbayashi, S., et al. 1990. Nihon Yakurigaku Zasshi. 96: 255-63. PMID: 2279713
- [The synthesis of 4'-(2-carboxyethyl)phenyl trans-4-aminomethyl cyclohexane carboxylate hydrochloride (cetraxate hydrochloride) by means of enzymatic debenzylation]. | Kuroda, H., et al. 1989. Yakugaku Zasshi. 109: 157-62. PMID: 2754616
- Inhibitory effect of prolonged oral administration of cetraxate hydrochloride on experimentally-induced intestinal metaplasia in Wistar rats. | Tatsuta, M., et al. 1987. Arzneimittelforschung. 37: 1045-8. PMID: 3435599
- Properties and localization of phospholipase A2 activity in rat stomach. | Hirohara, J., et al. 1987. Biochim Biophys Acta. 919: 231-8. PMID: 3593746
- Lineage of drug discovery research on fluorinated pyrimidines: chronicle of the achievements accomplished by Professor Setsuro Fujii. | Maehara, Y., et al. 2023. Int J Clin Oncol. 28: 613-624. PMID: 36961615
- [Synthesis and antiulcer activity of 2-amino-8H-indeno[1,2-d]thiazole derivatives]. | Inoue, H., et al. 1994. Yakugaku Zasshi. 114: 523-32. PMID: 7932097
- Anti-ulcer agent, cetraxate hydrochloride (Neuer), prevents subcellular redistribution of lysosomal enzyme in caerulein-induced pancreatitis in the rat. | Hirano, T. and Takeuchi, S. 1994. J Int Med Res. 22: 107-12. PMID: 8020637
- Geranylgeranylacetone and cetraxate hydrochloride increase UDP-galactosyltransferase activity in rat gastric mucosa. | Mikami, Y., et al. 1997. Acta Med Okayama. 51: 245-9. PMID: 9359921
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cetraxate, Hydrochloride, 10 mg | sc-211059 | 10 mg | $140.00 |