Molecular structure of Peroxisome Proliferator, Cetaben, CAS Number: 55986-43-1
Peroxisome Proliferator, Cetaben (CAS 55986-43-1)
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Alternate Names:
Hexadecylamino-p-amino Benzoic Acid
Application:
Peroxisome Proliferator, Cetaben is a compound that can permeate the cell and act independent of the PPARα
CAS Number:
55986-43-1
Purity:
>98%
Molecular Weight:
361.6
Molecular Formula:
C23H39NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Peroxisome Proliferator, Cetaben is a compound that can permeate the cell and act independent of the peroxisome proliferator-activated receptor alpha (PPARalpha). In addition, it may act to inhibit the activity of acyl-CoA:cholesterol acyltransferase (ACAT). The compound has hypolipidemic activity and research shows that it can reduce serum triglyceride and cholesterol concentrations in rats. It has the ability to inhibit cholesterol production in human hepatoma Hep-G2 cells, which can cause reversible changes to the Golgi morphology.
Peroxisome Proliferator, Cetaben (CAS 55986-43-1) References
- Cetaben-induced changes on the morphology and peroxisomal enzymes in MH1C1 rat hepatoma cells and HepG2 human hepatoblastoma cells. | Kovacs, W., et al. 2001. Histochem Cell Biol. 115: 509-19. PMID: 11455451
- Comparative effects of cetaben (PHB) and dichlormethylene diphosphonate (Cl2MDP) on the development of atherosclerosis in the cynomolgus monkey. | Hollander, W., et al. 1978. Atherosclerosis. 31: 307-25. PMID: 152632
- The hypolipidemic compound cetaben induces changes in Golgi morphology and vesicle movement. | Kovacs, WJ., et al. 2004. Histochem Cell Biol. 122: 95-109. PMID: 15322860
- Atherosclerosis mouse model induced by a high-cholesterol diet supplemented with beta-aminopropionitrile: effects of various anti-atherosclerotic agents on the biochemical parameters. | Yamaguchi, Y., et al. 1990. Jpn J Pharmacol. 54: 187-96. PMID: 2077185
- Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays. | Lee, JA., et al. 2015. PLoS One. 10: e0130796. PMID: 26177200
- Potential antiatherosclerotic agents. 2. (Aralkylamino)- and (alkylamino) benzoic acid analogues of cetaben. | Albright, JD., et al. 1983. J Med Chem. 26: 1378-93. PMID: 6604816
- Potential antiatherosclerotic agents. 3. Substituted benzoic and non benzoic acid analogues of cetaben. | Albright, JD., et al. 1983. J Med Chem. 26: 1393-411. PMID: 6604817
- Potential antiatherosclerotic agents. 4. [(Functionalized-alkyl)amino]benzoic acid analogues of cetaben. | DeVries, VG., et al. 1983. J Med Chem. 26: 1411-21. PMID: 6604818
- Cetaben versus clofibrate: comparison of toxicity and peroxisome proliferation in rats. | Fort, FL., et al. 1983. Toxicology. 28: 305-11. PMID: 6606240
- Micellar solubilization of cetaben sodium in surfactant and lipid solutions. | Chow, SL. and Sims, BE. 1981. J Pharm Sci. 70: 924-6. PMID: 6975813
- Cetaben is an exceptional type of peroxisome proliferator. | Chandoga, J., et al. 1994. Int J Biochem. 26: 679-96. PMID: 8005353
- Cetaben and fibrates both influence the activities of peroxisomal enzymes in different ways. | Chandoga, J., et al. 1994. Biochem Pharmacol. 47: 515-9. PMID: 8117320
- Differential induction of peroxisomal enzymes by hypolipidaemics in human (HepG2) and rat (MH1C1) hepatoma cell lines. | Stangl, H., et al. 1995. Eur J Clin Chem Clin Biochem. 33: 775-83. PMID: 8620053
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ACAT.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Peroxisome Proliferator, Cetaben, 10 mg | sc-203185 | 10 mg | $76.00 |