Cepharanthine (CAS 481-49-2)
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Cepharanthine is a compound that functions as a calcium channel blocker, inhibiting the influx of calcium ions into cells. It also acts as a P-glycoprotein inhibitor, preventing the efflux of certain substances from cells. At the molecular level, Cepharanthine interacts with specific cellular proteins and receptors, modulating their activity and influencing various cellular processes. Cepharanthine may affect the expression of certain genes and proteins, leading to alterations in cellular function. Cepharanthine displays antioxidant properties, scavenging free radicals and reducing oxidative stress within cells. Its mechanism of action involves the modulation of various signaling pathways and cellular processes, ultimately impacting cell function and viability. Cepharanthine plays a role in modulating cellular physiology and function, making it a subject of interest in experimental research applications.
Cepharanthine (CAS 481-49-2) References
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- Cepharanthine: a review of the antiviral potential of a Japanese-approved alopecia drug in COVID-19. | Rogosnitzky, M., et al. 2020. Pharmacol Rep. 72: 1509-1516. PMID: 32700247
- Inhibition of herpes simplex virus 1 by cepharanthine via promoting cellular autophagy through up-regulation of STING/TBK1/P62 pathway. | Liu, Y., et al. 2021. Antiviral Res. 193: 105143. PMID: 34303748
- Cepharanthine, a novel selective ANO1 inhibitor with potential for lung adenocarcinoma therapy. | Zhang, X., et al. 2021. Biochim Biophys Acta Mol Cell Res. 1868: 119132. PMID: 34450215
- Cepharanthine Regulates Autophagy via Activating the p38 Signaling Pathway in Lung Adenocarcinoma Cells. | Li, G., et al. 2022. Anticancer Agents Med Chem. 22: 1523-1529. PMID: 34477532
- Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis. | Gao, S., et al. 2022. Oxid Med Cell Longev. 2022: 4295208. PMID: 35186185
- Cepharanthine ameliorates dextran sulphate sodium-induced colitis through modulating gut microbiota. | Wang, HG., et al. 2022. Microb Biotechnol. 15: 2208-2222. PMID: 35439340
- Antinociceptive activities and mechanism of action of Cepharanthine. | Wei, XY., et al. 2022. Biochem Biophys Res Commun. 614: 219-224. PMID: 35636221
- Cepharanthine Ameliorates Chondrocytic Inflammation and Osteoarthritis via Regulating the MAPK/NF-κB-Autophagy Pathway. | Yao, M., et al. 2022. Front Pharmacol. 13: 854239. PMID: 35800437
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cepharanthine, 100 mg | sc-391213 | 100 mg | $45.00 | |||
Cepharanthine, 500 mg | sc-391213A | 500 mg | $150.00 |