Molecular structure of Cephalosporin C zinc salt, CAS Number: 59143-60-1
Cephalosporin C zinc salt (CAS 59143-60-1)
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Alternate Names:
Cephalosporin C zinc salt is a member of the Cephalosporin antibiotic family.
Application:
Cephalosporin C zinc salt is an antibiotic and inhibitor of SAMHD1 with an IC50 of 1.1 µM, 200x more potent than the Na+ salt form of Cephalosporin C.
CAS Number:
59143-60-1
Molecular Weight:
478.78
Molecular Formula:
C16H19N3O8S•Zn
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Cephalosporin C zinc salt is an antibiotic used to study the effect of transpeptidase expression, binding, and inhibition on bacterial cell wall mucopeptide synthesis. As is expected of a Cephalosporin, it will disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. Cephalosporin C and Cephalosporin C zinc salt in particular have been used to determine activity during stopped-flow Fluorescence spectrometric measurements of association.
Cephalosporin C zinc salt (CAS 59143-60-1) References
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- Multichannel liquid chromatography-tandem mass spectrometry cocktail method for comprehensive substrate characterization of multidrug resistance-associated protein 4 transporter. | Uchida, Y., et al. 2007. Pharm Res. 24: 2281-96. PMID: 17939016
- Structural insight into the kinetics and DeltaCp of interactions between TEM-1 beta-lactamase and beta-lactamase inhibitory protein (BLIP). | Wang, J., et al. 2009. J Biol Chem. 284: 595-609. PMID: 18840610
- Stimulation of cephalosporin C production in Acremonium chrysogenum M35 by glycerol. | Shin, HY., et al. 2010. Bioresour Technol. 101: 4549-53. PMID: 20171092
- Utilization of glycerol as cysteine and carbon sources for cephalosporin C production by Acremonium chrysogenum M35 in methionine-unsupplemented culture. | Shin, HY., et al. 2011. J Biotechnol. 151: 363-8. PMID: 21219942
- Biochemical characterization and relative expression levels of multiple carbohydrate esterases of the xylanolytic rumen bacterium Prevotella ruminicola 23 grown on an ester-enriched substrate. | Kabel, MA., et al. 2011. Appl Environ Microbiol. 77: 5671-81. PMID: 21742923
- Expression of cefF significantly decreased deacetoxycephalosporin C formation during cephalosporin C production in Acremonium chrysogenum. | An, Y., et al. 2012. J Ind Microbiol Biotechnol. 39: 269-74. PMID: 21866341
- Production of cephalosporin C using crude glycerol in fed-batch culture of Acremonium chrysogenum M35. | Shin, HY., et al. 2011. J Microbiol. 49: 753-8. PMID: 22068491
- Enhancing effect of lysine combined with other compounds on cephamycin C production in Streptomyces clavuligerus. | Leite, CA., et al. 2013. BMC Microbiol. 13: 296. PMID: 24359569
- A High-Throughput Enzyme-Coupled Assay for SAMHD1 dNTPase. | Seamon, KJ. and Stivers, JT. 2015. J Biomol Screen. 20: 801-9. PMID: 25755265
- Utilization of algal sugars and glycerol for enhanced cephalosporin C production by Acremonium chrysogenum M35. | Lee, JH., et al. 2017. Lett Appl Microbiol. 64: 66-72. PMID: 27736007
- The two-component system CepRS regulates the cephamycin C biosynthesis in Streptomyces clavuligerus F613-1. | Fu, J., et al. 2019. AMB Express. 9: 118. PMID: 31352530
- Small Molecule Receptor Binding Inhibitors with In Vivo Efficacy against Botulinum Neurotoxin Serotypes A and E. | Ben David, A., et al. 2021. Int J Mol Sci. 22: PMID: 34445283
- Methionine metabolism and cephalosporin C synthesis in Cephalosporium acremonium. D-amino acid oxidase. | Benz, F., et al. 1971. Eur J Biochem. 20: 81-8. PMID: 4397084
- Heritable mass conversion of a mutant penicillinase-negative culture of Bacillus cereus to a positive fully de-repressed state. | Pollock, MR. and Fleming, J. 1969. J Gen Microbiol. 59: 303-16. PMID: 4984853
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cephalosporin C zinc salt, 5 g | sc-396796 | 5 g | $913.00 | |||
Cephalosporin C zinc salt, 25 g | sc-396796A | 25 g | $4142.00 |