Cephalexin Monohydrate (CAS 23325-78-2)

Cephalexin Monohydrate, a beta-lactam antibiotic within the cephalosporin class, plays a role in the study of bacterial resistance mechanisms and the development of novel antimicrobial strategies. Its mechanism of action is centered around the inhibition of bacterial cell wall synthesis, a vital process for bacterial growth and survival. This is achieved through its binding to penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. By attaching to these PBPs, Cephalexin Monohydrate disrupts the final transpeptidation step of peptidoglycan synthesis, leading to the weakening of the cell wall and ultimately causing bacterial cell lysis. In research, its effectiveness against a broad spectrum of Gram-positive and some Gram-negative bacteria makes it an invaluable tool for studying the dynamics of bacterial growth, the evolution of antibiotic resistance, and the testing of new compounds for their potential to inhibit bacterial cell wall synthesis. Furthermore, its well-characterized mechanism and spectrum of activity provide a comparative benchmark for the evaluation of new cephalosporins and other beta-lactam antibiotics, enhancing our understanding of bacterial pathogenesis and the development of more effective antimicrobial agents.