Molecular structure of Cephalexin, CAS Number: 15686-71-2
Cephalexin (CAS 15686-71-2)
Alternate Names:
Cefalexin; Cephacillin
Application:
Cephalexin is a semi-synthetic, cephalosporin antibiotic
CAS Number:
15686-71-2
Molecular Weight:
347.38
Molecular Formula:
C16H17N3O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Cephalexin inhibits the synthesis of bacterial cell walls. It achieves this by binding to penicillin-binding proteins (PBPs) on the bacterial cell membrane, which are essential for the cross-linking of peptidoglycan chains during cell wall synthesis. By binding to PBPs, Cephalexin disrupts the formation of the cell wall, leading to the weakening and eventual lysis of the bacterial cell. This mechanism of action ultimately results in the inhibition of bacterial growth and reproduction. Cephalexin is able to penetrate the bacterial cell membrane, allowing it to exert its bactericidal effects intracellularly.
Cephalexin (CAS 15686-71-2) References
- Polarographic behavior of cephalexin and its determination in pharmaceuticals and human serum. | Xu, M., et al. 2004. J Pharm Biomed Anal. 35: 1075-81. PMID: 15336354
- Dermal drug levels of antibiotic (cephalexin) determined by electroporation and transcutaneous sampling (ETS) technique. | Sammeta, SM., et al. 2009. J Pharm Sci. 98: 2677-85. PMID: 19067398
- Cephalexin in ponies: a preliminary investigation. | Lees, P., et al. 1990. Vet Rec. 126: 635-7. PMID: 2382364
- Controlled release of antimicrobial Cephalexin drug from silica microparticles. | Bhaskara Rao, BV., et al. 2014. Mater Sci Eng C Mater Biol Appl. 34: 9-14. PMID: 24268227
- Synthesis and application of cephalexin imprinted polymer for solid phase extraction in milk. | Lata, K., et al. 2015. Food Chem. 184: 176-82. PMID: 25872441
- Cephalexin-induced haemolytic anaemia: A case report. | Thiessen, K. and Kraleti, S. 2017. J Clin Pharm Ther. 42: 615-617. PMID: 28474415
- Adsorption of cephalexin in aqueous media by graphene oxide: kinetics, isotherm, and thermodynamics. | Wernke, G., et al. 2020. Environ Sci Pollut Res Int. 27: 4725-4736. PMID: 31845249
- In-vitro activity of cefaclor, cephalexin and ampicillin against 2458 clinical isolates of Haemophilus influenzae. | Powell, M. and Williams, JD. 1988. J Antimicrob Chemother. 21: 27-31. PMID: 3258594
- Probenecid effects on cephalexin pharmacokinetics and pharmacodynamics in healthy volunteers. | Everts, RJ., et al. 2021. J Infect. 83: 182-189. PMID: 34081957
- High performance liquid chromatographic analysis of cephalexin in serum and urine. | Najib, NM., et al. 1987. J Clin Pharm Ther. 12: 419-26. PMID: 3440814
- Therapeutic efficacy of cefadroxil and cephalexin for pneumonia in a rat test model. | Chisholm, DR., et al. 1986. Antimicrob Agents Chemother. 30: 105-9. PMID: 3752972
- Cephalexin levels in human bile in presence of biliary tract disease. | Sales, JE., et al. 1972. Br Med J. 3: 441-3. PMID: 5069220
- Cephalexin levels in serum, synovial fluid and joint tissues after oral administration. | Jalava, S., et al. 1977. Scand J Rheumatol. 6: 250-2. PMID: 607395
- In vitro susceptibility studies with cefaclor and cephalexin. | Scheld, WM., et al. 1977. Antimicrob Agents Chemother. 12: 290-2. PMID: 900924
- HPTLC assay of cephalexin and cefaclor in pharmaceuticals. | Agbaba, D., et al. 1998. Biomed Chromatogr. 12: 133-5. PMID: 9646911
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PEPT1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cephalexin, 5 g | sc-211053 | 5 g | $117.00 | |||
Cephalexin, 100 g | sc-211053A | 100 g | $128.00 | |||
Cephalexin, 250 g | sc-211053B | 250 g | $230.00 | |||
Cephalexin, 1 kg | sc-211053C | 1 kg | $465.00 |