cell surface-anchored protein Antibody (G-4): sc-398060
- cell surface-anchored protein Antibody (G-4) is a mouse monoclonal IgG2a κ cell surface-anchored protein antibody provided at 200 µg/ml
- raised against amino acids 294-494 mapping within an internal region of cell surface-anchored protein of Streptococcus equi subsp. equi 4047 origin
- cell surface-anchored protein Antibody (G-4) is recommended for detection of cell surface-anchored protein of Streptococcus equi subsp. equi 4047 origin by WB, IP, IF and ELISA
- Anti-cell surface-anchored protein Antibody (G-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for cell surface-anchored protein Antibody (G-4) for WB applications. These reagents are now offered in bundles with cell surface-anchored protein Antibody (G-4) (see ordering information below).
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Cell surface-anchored protein Antibody (G-4) is a mouse monoclonal IgG2a kappa light chain antibody that detects the cell surface-anchored protein of Streptococcus equi subsp. equi 4047 origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-cell surface-anchored protein antibody (G-4) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Cell surface-anchored protein (G-4) monoclonal antibody recognizes a protein that plays a crucial role in the pathogenesis of Streptococcus equi, as this protein is involved in bacterial adhesion to host cells, facilitating colonization and infection. This interaction is vital for bacterial establishment of disease, particularly in strangles, a highly contagious equine disease characterized by severe respiratory symptoms and lymphadenitis. Understanding cell surface-anchored protein function not only aids in developing diagnostic tools but also opens avenues for therapeutic interventions aimed at disrupting bacterial adhesion and preventing infection. Transmission primarily occurs through inhalation or direct contact with infected secretions, making cell surface-anchored protein research essential for controlling outbreaks in equine populations.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
cell surface-anchored protein Antibody (G-4) References:
- Getting to grips with strangles: an effective multi-component recombinant vaccine for the protection of horses from Streptococcus equi infection. | Guss, B., et al. 2009. PLoS Pathog. 5: e1000584. PMID: 19763180
- Molecular characterisation of 'strangles' outbreaks in the UK: the use of M-protein typing of Streptococcus equi ssp. equi. | Ivens, PA., et al. 2011. Equine Vet J. 43: 359-64. PMID: 21492215
- Association of Streptococcus equi with equine monocytes. | Mérant, C., et al. 2011. Vet Immunol Immunopathol. 143: 83-6. PMID: 21752476
- Streptococcus equi: a pathogen restricted to one host. | Waller, AS., et al. 2011. J Med Microbiol. 60: 1231-1240. PMID: 21757503
- Streptococcus equi subspecies equi infection (strangles) in horses. | Boyle, A. 2011. Compend Contin Educ Vet. 33: E1-7; quiz E8. PMID: 21870348
- Antiphagocytic function of an IgG glycosyl hydrolase from Streptococcus equi subsp. equi and its use as a vaccine component. | Flock, M., et al. 2012. Infect Immun. 80: 2914-9. PMID: 22615244
- Development of a novel mucosal vaccine against strangles by supercritical enhanced atomization spray-drying of Streptococcus equi extracts and evaluation in a mouse model. | Rodrigues, MA., et al. 2012. Eur J Pharm Biopharm. 82: 392-400. PMID: 22841882
- Detection of Streptococcus equi subspecies equi using a triplex qPCR assay. | Webb, K., et al. 2013. Vet J. 195: 300-4. PMID: 22884566
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
cell surface-anchored protein Antibody (G-4) | sc-398060 | 200 µg/ml | $316.00 | |||
cell surface-anchored protein Antibody (G-4): m-IgG Fc BP-HRP Bundle | sc-530685 | 200 µg Ab; 10 µg BP | $354.00 | |||
cell surface-anchored protein Antibody (G-4): m-IgGκ BP-HRP Bundle | sc-524205 | 200 µg Ab, 40 µg BP | $354.00 | |||
cell surface-anchored protein Antibody (G-4): m-IgG2a BP-HRP Bundle | sc-547561 | 200 µg Ab; 10 µg BP | $354.00 | |||
cell surface-anchored protein Antibody (G-4) AC | sc-398060 AC | 500 µg/ml, 25% agarose | $416.00 | |||
cell surface-anchored protein Antibody (G-4) HRP | sc-398060 HRP | 200 µg/ml | $316.00 | |||
cell surface-anchored protein Antibody (G-4) FITC | sc-398060 FITC | 200 µg/ml | $330.00 | |||
cell surface-anchored protein Antibody (G-4) PE | sc-398060 PE | 200 µg/ml | $343.00 | |||
cell surface-anchored protein Antibody (G-4) Alexa Fluor® 488 | sc-398060 AF488 | 200 µg/ml | $357.00 | |||
cell surface-anchored protein Antibody (G-4) Alexa Fluor® 546 | sc-398060 AF546 | 200 µg/ml | $357.00 | |||
cell surface-anchored protein Antibody (G-4) Alexa Fluor® 594 | sc-398060 AF594 | 200 µg/ml | $357.00 | |||
cell surface-anchored protein Antibody (G-4) Alexa Fluor® 647 | sc-398060 AF647 | 200 µg/ml | $357.00 | |||
cell surface-anchored protein Antibody (G-4) Alexa Fluor® 680 | sc-398060 AF680 | 200 µg/ml | $357.00 | |||
cell surface-anchored protein Antibody (G-4) Alexa Fluor® 790 | sc-398060 AF790 | 200 µg/ml | $357.00 |