Molecular structure of Cefuroxime Sodium Salt, CAS Number: 56238-63-2
Cefuroxime Sodium Salt (CAS 56238-63-2)
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Application:
Cefuroxime Sodium Salt is an antibacterial compound
CAS Number:
56238-63-2
Molecular Weight:
446.4
Molecular Formula:
C16H15N4NaO8S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Cefuroxime Sodium Salt is a cephalosporin antibiotic with broad-spectrum activity against Gram-positive and Gram-negative bacteria including S. pyogenes, S. pneumoniae, S. viridans, E. coli, P. mirabilis, H. influenzae, and N. gonorrhoeae (mean MICs = 0.005-8.2 μg/ml). Like other cephalosporins, Cefuroxime inhibits peptidoglycan crosslinking and bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). It is resistant to hydrolysis by bacterial β-lactamases, increasing its efficacy against β-lactamase producing Gram-negative bacteria. Cefuroxime Sodium Salt has also been found to have a variety of effects on the immune system, including the induction of cytokine production, the activation of macrophages, and the stimulation of the production of antibodies.
Cefuroxime Sodium Salt (CAS 56238-63-2) References
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- Bioequivalence and population pharmacokinetic modeling of two forms of antibiotic, cefuroxime lysine and cefuroxime sodium, after intravenous infusion in beagle dogs. | Zhao, L., et al. 2012. J Biomed Biotechnol. 2012: 507294. PMID: 22911056
- Optimization and validation of spectrofluorimetric method for determination of cefadroxile and cefuroxime sodium in pharmaceutical formulations. | Elbashir, AA., et al. 2013. Luminescence. 28: 490-5. PMID: 23345111
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- Role of liquid membrane phenomenon in the anti-bacterial activity of Cefuroxime Sodium. | Nagesh, C., et al. 2010. J Basic Clin Pharm. 1: 77-80. PMID: 24825969
- Compatibility of clindamycin phosphate with aztreonam in polypropylene syringes and with cefoperazone sodium, cefonicid sodium, and cefuroxime sodium in partial-fill glass bottles. | Marble, DA., et al. 1988. Drug Intell Clin Pharm. 22: 54-7. PMID: 3349921
- Pharmacokinetic Study of Coadministration with Cefuroxime Sodium for Injection Influencing ReDuNing Injection-Derived Seven Phytochemicals and Nine Metabolites in Rats. | Zhao, Q., et al. 2022. J Anal Methods Chem. 2022: 2565494. PMID: 35795192
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- Stability of cefuroxime sodium in some aqueous buffered solutions and intravenous admixtures. | Das Gupta, V. and Stewart, KR. 1986. J Clin Hosp Pharm. 11: 47-54. PMID: 3958213
- Preservative efficacy in cefuroxime and ceftazidime eye drop formulations. | Barnes, AR. and Nash, S. 1994. J Clin Pharm Ther. 19: 327-32. PMID: 7806604
- Stability and compatibility of admixtures of intravenous ciprofloxacin and selected drugs. | Elmore, RL., et al. 1996. Clin Ther. 18: 246-55. PMID: 8733985
- Long-term stability of cefuroxime and cefazolin sodium in intravenous infusions. | Galanti, LM., et al. 1996. J Clin Pharm Ther. 21: 185-9. PMID: 8873853
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cefuroxime Sodium Salt, 1 g | sc-217863 | 1 g | $105.00 |