Date published: 2026-4-24

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Cefuroxime-d3

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Application:
Cefuroxime-d3 is an antibacterial
Molecular Weight:
427.40
Molecular Formula:
C16H13D3N4O8S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cefuroxime-d3 is a deuterated form of cefuroxime, wherein three hydrogen atoms have been replaced with deuterium, a heavier isotope of hydrogen. This modification is particularly useful in research settings, especially within the realms of analytical and environmental chemistry. The inclusion of deuterium does not change the chemical structure of cefuroxime significantly but provides enhanced analytical properties. For instance, the deuterium atoms introduce a distinct mass difference that is highly beneficial in mass spectrometry, allowing for more precise and specific detection and quantification of cefuroxime in complex samples. This capability is crucial when studying the pharmacokinetics and environmental fateCefuroxime-d3 is a deuterated form of cefuroxime, wherein three hydrogen atoms have been replaced with deuterium, a heavier isotope of hydrogen. This modification is particularly useful in research settings, especially within the realms of analytical and environmental chemistry. The inclusion of deuterium does not change the chemical structure of cefuroxime significantly but provides enhanced analytical properties. For instance, the deuterium atoms introduce a distinct mass difference that is highly beneficial in mass spectrometry, allowing for more precise and specific detection and quantification of cefuroxime in complex samples. This capability is crucial when studying the pharmacokinetics and environmental fate of the molecule. Researchers utilize Cefuroxime-d3 in environmental sciences to track the degradation and movement of cefuroxime through ecosystems, helping to understand how such substances persist or break down in natural settings. Additionally, in analytical chemistry, Cefuroxime-d3 serves as an internal standard, improving the accuracy and reliability of data by compensating for variations in sample preparation and instrumental analysis. This makes it an invaluable tool for developing robust analytical methods that require high precision, such as those used in monitoring antibiotic contamination in water supplies and other environmental matrices.


Cefuroxime-d3 References

  1. An optimized SPE-LC-MS/MS method for antibiotics residue analysis in ground, surface and treated water samples by response surface methodology- central composite design.  |  Mirzaei, R., et al. 2017. J Environ Health Sci Eng. 15: 21. PMID: 29075502
  2. Occurrence and fate of most prescribed antibiotics in different water environments of Tehran, Iran.  |  Mirzaei, R., et al. 2018. Sci Total Environ. 619-620: 446-459. PMID: 29156265
  3. Lung Collapse during Mini-Thoracotomy Reduces Penetration of Cefuroxime to the Tissue: Interstitial Microdialysis Study in Animal Models.  |  Děrgel, M., et al. 2021. Surg Infect (Larchmt). 22: 283-291. PMID: 32633629
  4. Evaluation of cefuroxime concentration in the intrathecal and extrathecal compartments of the lumbar spine-an experimental study in pigs.  |  Kaspersen, AE., et al. 2023. Br J Pharmacol.. PMID: 36710378
  5. Screening of antibiotic residues in raw bovine milk in Lombardy, Italy: Microbial growth inhibition assay and LC-HRMS technique integration for an accurate monitoring.  |  Butovskaya, E., et al. 2023. Heliyon. 9: e15395. PMID: 37123980

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cefuroxime-d3, 1 mg

sc-217864
1 mg
$459.00