Date published: 2025-10-2

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Cefuroxime axetil (CAS 64544-07-6)

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CAS Number:
64544-07-6
Molecular Weight:
510.47
Molecular Formula:
C20H22N4O10S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cefuroxime axetil, abbreviated as CA, stands as a semi-synthetic cephalosporin antibiotic renowned for its efficacy in combating bacterial infections. Embracing the classification of a second-generation cephalosporin, Cefuroxime axetil exhibits a broad spectrum of activity, effectively targeting both Gram-positive and Gram-negative bacteria. Cefuroxime axetil operates by impeding the synthesis of bacterial cell walls. By binding to penicillin-binding proteins, which play a pivotal role in cell wall synthesis, Cefuroxime axetil disrupts the process of peptidoglycan cross-linking.


Cefuroxime axetil (CAS 64544-07-6) References

  1. Cefuroxime axetil: an updated review of its use in the management of bacterial infections.  |  Scott, LJ., et al. 2001. Drugs. 61: 1455-500. PMID: 11558834
  2. Oral cephalosporins.  |  Verhaegen, J. and Verbist, L. 1992. Acta Clin Belg. 47: 377-86. PMID: 1337810
  3. Cefuroxime axetil.  |  Dellamonica, P. 1994. Int J Antimicrob Agents. 4: 23-36. PMID: 18611587
  4. [Cefuroxime axetil, a new oral cephalosporin for treating infections of the ORL field: clinical synthesis].  |  Westphal, JF. 1990. Rev Laryngol Otol Rhinol (Bord). 111: 503-5. PMID: 2087617
  5. Cefuroxime axetil loaded solid lipid nanoparticles for enhanced activity against S. aureus biofilm.  |  Singh, B., et al. 2014. Colloids Surf B Biointerfaces. 121: 92-8. PMID: 24945607
  6. Diagnosis, Treatment, and Prevention of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis: A Review.  |  Sanchez, E., et al. 2016. JAMA. 315: 1767-77. PMID: 27115378
  7. Cefuroxime axetil.  |  Marx, MA. and Fant, WK. 1988. Drug Intell Clin Pharm. 22: 651-8. PMID: 3063476
  8. Cefuroxime axetil and penicillin V compared in the treatment of group A beta-hemolytic streptococcal pharyngitis.  |  Gooch, WM., et al. 1987. Clin Ther. 9: 670-7. PMID: 3125976
  9. Effects of cefuroxime axetil combined with Xingpi Yanger granules on the serum gastrin, motilin, and somatostatin levels in children with upper respiratory tract infection accompanied by diarrhea: results of a randomized trial.  |  Ren, X., et al. 2021. Transl Pediatr. 10: 2106-2113. PMID: 34584881
  10. Optimization of a Cefuroxime Axetil-Loaded Liquid Self-Nanoemulsifying Drug Delivery System: Enhanced Solubility, Dissolution and Caco-2 Cell Uptake.  |  Khan, AA., et al. 2022. Pharmaceutics. 14: PMID: 35456606
  11. In Vivo Evaluation of Cefuroxime Axetil-Loaded Bioadhesive Nanoparticles to Treat Haemophilus influenzae-Induced Otitis Media.  |  Lin, H., et al. 2022. Front Bioeng Biotechnol. 10: 884797. PMID: 35573224
  12. Cefuroxime axetil in the treatment of sinusitis. A review.  |  Pakes, GE., et al. 1994. Arch Fam Med. 3: 165-75. PMID: 7994439
  13. Cefuroxime axetil. A review of its antibacterial activity, pharmacokinetic properties and therapeutic efficacy.  |  Perry, CM. and Brogden, RN. 1996. Drugs. 52: 125-58. PMID: 8799689

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cefuroxime axetil, 100 mg

sc-278826
100 mg
$200.00