Molecular structure of Cefuroxime, CAS Number: 55268-75-2
Cefuroxime (CAS 55268-75-2)
See product citations (3)
Alternate Names:
Cephuroxime; Cefuroxim; Cefuroximo
Application:
Cefuroxime is a second-generation cephalosporin antibiotic
CAS Number:
55268-75-2
Molecular Weight:
424.39
Molecular Formula:
C16H16N4O8S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Cefuroxime is less susceptible to beta-lactamase, as with the other cephalosporins, although as a second-generation variety. Hence, it may potentially have greater activity against Haemophilus influenzae, Neisseria gonorrhoeae, and Lyme disease. Unlike most other second-generation cephalosporins, cefuroxime can cross the blood-brain barrier.
Cefuroxime (CAS 55268-75-2) References
- Simultaneous measurement of cefuroxime in rat blood and brain by microdialysis and microbore liquid chromatography. Application to pharmacokinetics. | Tsai, TH., et al. 1999. J Chromatogr B Biomed Sci Appl. 735: 25-31. PMID: 10630887
- Blood concentrations of cefuroxime in cardiopulmonary bypass surgery. | Bertholee, D., et al. 2013. Int J Clin Pharm. 35: 798-804. PMID: 23794078
- Targeting cefuroxime plasma concentrations during coronary artery bypass graft surgery with cardiopulmonary bypass. | Aalbers, M., et al. 2015. Int J Clin Pharm. 37: 592-8. PMID: 25791346
- Pharmacokinetics of cefuroxime after intravenous, intramuscular, and subcutaneous administration to dogs. | Albarellos, GA., et al. 2016. J Vet Pharmacol Ther. 39: 40-4. PMID: 25982523
- Stability of 10 mg/mL cefuroxime solution for intracameral injection in commonly used polypropylene syringes and new ready-to-use cyclic olefin copolymer sterile vials using the LC-UV stability-indicating method. | Feutry, F., et al. 2016. Drug Dev Ind Pharm. 42: 166-174. PMID: 26006333
- Effects of Implant-Associated Osteomyelitis on Cefuroxime Bone Pharmacokinetics: Assessment in a Porcine Model. | Tøttrup, M., et al. 2016. J Bone Joint Surg Am. 98: 363-9. PMID: 26935458
- Is empirical use of the antibiotic combination of cefuroxime and clavulanic acid rational? | Gupta, H., et al. 2019. J Glob Antimicrob Resist. 16: 150-151. PMID: 30611930
- Co-processing of cefuroxime axetil by spray drying technique for improving compressibility and flow property. | Rathod, P., et al. 2019. Drug Dev Ind Pharm. 45: 767-774. PMID: 30722705
- Uptake and pharmacokinetics of cefuroxime in rabbits after intravitreal, intracameral, and topical dosing: relevance to human ocular injection of cefuroxime. | Jairam, RK., et al. 2020. Xenobiotica. 50: 339-345. PMID: 31144563
- Population pharmacokinetics of cefuroxime and uptake into hip and spine bone of patients undergoing orthopaedic surgery. | Gergs, U., et al. 2020. J Pharm Pharmacol. 72: 364-370. PMID: 31858616
- Fabrication and antibacterial properties of cefuroxime-loaded TiO2 nanotubes. | Niu, X., et al. 2020. Appl Microbiol Biotechnol. 104: 2947-2955. PMID: 32055911
- Molecular Structure of Cefuroxime Axetil Complexes with α-, β-, γ-, and 2-Hydroxypropyl-β-Cyclodextrins: Molecular Simulations and Raman Spectroscopic and Imaging Studies. | Gieroba, B., et al. 2021. Int J Mol Sci. 22: PMID: 34063471
- A fast, cost-saving and sensitive method for determination of cefuroxime in plasma by HPLC with ultraviolet detection. | Hernandis, V., et al. 2021. Biomed Chromatogr. 35: e5188. PMID: 34081795
- Cefuroxime concentrations in the anterior and posterior column of the lumbar spine - an experimental porcine study. | Hvistendahl, MA., et al. 2022. Spine J. 22: 1434-1441. PMID: 35671945
- Nonlinear intestinal absorption kinetics of cefuroxime axetil in rats. | Ruiz-Balaguer, N., et al. 1997. Antimicrob Agents Chemother. 41: 445-8. PMID: 9021205
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cefuroxime, 25 mg | sc-234294C | 25 mg | $90.00 | |||
Cefuroxime, 100 mg | sc-234294 | 100 mg | $214.00 | |||
Cefuroxime, 250 mg | sc-234294A | 250 mg | $397.00 | |||
Cefuroxime, 1 g | sc-234294B | 1 g | $1255.00 |