Molecular structure of Ceftazidime Pentahydrate, CAS Number: 78439-06-2
Ceftazidime Pentahydrate (CAS 78439-06-2)
Alternate Names:
1-[[(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium Inner Salt Pentahydrate; Biotum; Ceftacidin; Fortam; Fortaz; Fortum; GR 20263; Modacin
Application:
Ceftazidime Pentahydrate is a third generation cephalosporin antibiotic
CAS Number:
78439-06-2
Purity:
≥98%
Molecular Weight:
636.65
Molecular Formula:
C22H32N6O12S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ceftazidime Pentahydrate is a third generation cephalosporin antibiotic. Cephalosporins are composed of 7-aminocephalosporanic acids and are of different sizes depending on their side chain substituents. Studies show that Ceftazidime Pentahydrate has greater activity against Pseudomonas aeruginosa than it does against gram-positive cocci.
Ceftazidime Pentahydrate (CAS 78439-06-2) References
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- LC determination of cephalosporins in in vitro rat intestinal sac absorption model. | Sharma, P., et al. 2002. J Pharm Biomed Anal. 27: 39-50. PMID: 11682209
- Relationship between lipophilicity of BCS class III and IV drugs and the functional activity of peroral absorption enhancers. | Sharma, P., et al. 2005. Farmaco. 60: 870-3. PMID: 16182296
- Absorption enhancement, mechanistic and toxicity studies of medium chain fatty acids, cyclodextrins and bile salts as peroral absorption enhancers. | Sharma, P., et al. 2005. Farmaco. 60: 884-93. PMID: 16226752
- Use of charge-transfer complexation in the spectrophotometric analysis of certain cephalosporins. | Saleh, GA., et al. 2001. Talanta. 54: 1205-15. PMID: 18968341
- Antibiotic-eluting bioresorbable composite fibers for wound healing applications: microstructure, drug delivery and mechanical properties. | Elsner, JJ. and Zilberman, M. 2009. Acta Biomater. 5: 2872-83. PMID: 19416766
- Kinetic spectrophotometric determination of certain cephalosporins in pharmaceutical formulations. | Omar, MA., et al. 2009. Int J Anal Chem. 2009: 596379. PMID: 20140078
- Chronokinetics of ceftazidime after intramuscular administration to dogs. | Monfrinotti, A., et al. 2010. Chronobiol Int. 27: 549-59. PMID: 20524800
- Invariom modeling of ceftazidime pentahydrate: molecular properties from a 200 second synchrotron microcrystal experiment. | Schürmann, CJ., et al. 2012. Acta Crystallogr B. 68: 313-7. PMID: 22610682
- Drug analysis by near-infra-red reflectance spectroscopy. Determination of the active ingredient and water content in antibiotic powders. | Lonardi, S., et al. 1989. J Pharm Biomed Anal. 7: 303-8. PMID: 2488631
- Ceftazidime pentahydrate/avibactam sodium, Isavuconazonium sulfate, and Daclatasvir dihydrochloride. | Hussar, DA. and Friedman, J. 2016. J Am Pharm Assoc (2003). 56: 100-3. PMID: 26802929
- Interference by cephalosporins with creatinine measurement by desk-top analyzers. | Nanji, AA., et al. 1987. Eur J Clin Pharmacol. 33: 427-9. PMID: 3443149
- Intravenous antimicrobial administration through peripheral venous catheters - establishing risk profiles from an analysis of 5252 devices. | Larsen, EN., et al. 2022. Int J Antimicrob Agents. 59: 106552. PMID: 35183678
- Comparative in vitro activities of third-generation cephalosporins. | Fass, RJ. 1983. Arch Intern Med. 143: 1743-5. PMID: 6615095
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ceftazidime Pentahydrate, 1 g | sc-217862 | 1 g | $106.00 | |||
Ceftazidime Pentahydrate, 5 g | sc-217862A | 5 g | $443.00 | |||
Ceftazidime Pentahydrate, 25 g | sc-217862B | 25 g | $2003.00 |