Ceftazidime dihydrochloride (CAS 73547-70-3)
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Ceftazidime dihydrochloride is an antimicrobial compound that belongs to the cephalosporin class of antibiotics, effective against a broad range of Gram-negative and some Gram-positive bacteria, including Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterobacter, and Serratia marcescens. It is used in the research of bacterial infections, particularly those caused by Gram-negative bacteria. Ceftazidime dihydrochloride is widely employed to study bacterial resistance to antibiotics, bacterial metabolism, and the development of new antibiotics. Its mechanism of action involves binding to penicillin-binding proteins (PBPs) responsible for bacterial cell wall synthesis, thus inhibiting the formation of the cell wall, which ultimately leads to bacterial death.
Ceftazidime dihydrochloride (CAS 73547-70-3) References
- Synthesis of [(2)H6]ceftazidime as a stable isotopically labeled internal standard. | Bian, L. and Bushby, N. 2015. J Labelled Comp Radiopharm. 58: 313-6. PMID: 26017617
- Development and validation of a UPLC-PDA method for quantifying ceftazidime in dried blood spots. | Lv, J., et al. 2024. J Pharm Biomed Anal. 239: 115928. PMID: 38134705
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ceftazidime dihydrochloride, 1 g | sc-278824 | 1 g | $1100.00 |