Molecular structure of Cefsulodin sodium salt, CAS Number: 52152-93-9
Cefsulodin sodium salt (CAS 52152-93-9)
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Application:
Cefsulodin sodium salt is a β lactam antibiotic
CAS Number:
52152-93-9
Purity:
≥98%
Molecular Weight:
554.53
Molecular Formula:
C22H19N4NaO8S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Cefsulodin sodium salt hydrate, a third-generation beta-lactam compound and part of the cephems subgroup, exhibits a mechanism consistent with many beta-lactam compounds by blocking the synthesis of bacterial cell walls. It does this through a competitive inhibition of the penicillin-binding proteins (PBPs), specifically interfering with the crosslinking of peptidoglycan chains necessary for cell wall integrity during the final stages of assembly. This action has been observed to affect various bacteria, showcasing a broad-spectrum nature. However, its effectiveness varies, as seen with cefsulodin-resistant mutants of Pseudomonas aeruginosa, suggesting that it targets multiple PBPs, including PBP3, PBP1A, and PBP1B, to exert its effects.
Cefsulodin sodium salt (CAS 52152-93-9) References
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- Cell cycle-independent lysis of Escherichia coli by cefsulodin, an inhibitor of penicillin-binding proteins 1a and 1b. | Jacoby, GH. and Young, KD. 1991. J Bacteriol. 173: 1-5. PMID: 1987110
- Involvement of multidrug resistance-associated protein 4 in efflux transport of prostaglandin E(2) across mouse blood-brain barrier and its inhibition by intravenous administration of cephalosporins. | Akanuma, S., et al. 2010. J Pharmacol Exp Ther. 333: 912-9. PMID: 20194529
- Resistance of Pseudomonas aeruginosa to cefsulodin: modification of penicillin-binding protein 3 and mapping of its chromosomal gene. | Gotoh, N., et al. 1990. J Antimicrob Chemother. 25: 513-23. PMID: 2112536
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- Emission of extensively-drug-resistant Acinetobacter baumannii from hospital settings to the natural environment. | Seruga Music, M., et al. 2017. J Hosp Infect. 96: 323-327. PMID: 28532975
- Transmission and survival of carbapenem-resistant Acinetobacter baumannii outside hospital setting. | Kovacic, A., et al. 2017. Int Microbiol. 20: 165-169. PMID: 29529327
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cefsulodin sodium salt, 100 mg | sc-257222 | 100 mg | $71.00 | |||
Cefsulodin sodium salt, 250 mg | sc-257222A | 250 mg | $116.00 | |||
Cefsulodin sodium salt, 1 g | sc-257222B | 1 g | $352.00 | |||
Cefsulodin sodium salt, 5 g | sc-257222C | 5 g | $1061.00 | |||
Cefsulodin sodium salt, 25 g | sc-257222D | 25 g | $4080.00 |