Date published: 2025-12-5

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Cefquinome (CAS 84957-30-2)

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CAS Number:
84957-30-2
Purity:
≥90%
Molecular Weight:
528.60
Molecular Formula:
C23H24N6O5S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cefquinome, a widely employed compound in scientific studies, has proven instrumental in examining the impact on the synthesis of bacterial cell walls. Its mechanism of action involves inhibiting the activity of penicillin-binding proteins (PBPs) situated on the bacterial cell wall. By doing so, it hampers the synthesis of the cell wall, ultimately leading to the demise of the bacteria.


Cefquinome (CAS 84957-30-2) References

  1. Pharmacodynamics of cefquinome in a neutropenic mouse thigh model of Staphylococcus aureus infection.  |  Wang, J., et al. 2014. Antimicrob Agents Chemother. 58: 3008-12. PMID: 24614373
  2. Pharmacokinetic profile of cefquinome after oral subchronic flubendiamide exposure and in vitro plasma protein binding in buffalo calves.  |  Venkatachalam, D. and Dumka, VK. 2015. Environ Toxicol Pharmacol. 39: 321-6. PMID: 25546120
  3. Pharmacokinetic/pharmacodynamic assessment of cefquinome against Actinobacillus Pleuropneumoniae in a piglet tissue cage infection model.  |  Zhang, L., et al. 2018. Vet Microbiol. 219: 100-106. PMID: 29778180
  4. Residue concentration of cefquinome after intramammary dry cow therapy and short dry periods.  |  Bachmann, J., et al. 2018. J Dairy Sci. 101: 7540-7550. PMID: 29859692
  5. Pharmacokinetic/pharmacodynamic integration of cefquinome against Pasteurella Multocida in a piglet tissue cage model.  |  Zhang, L., et al. 2019. J Vet Pharmacol Ther. 42: 60-66. PMID: 30407642
  6. Pharmacokinetics and bioavailability of cefquinome and ceftriaxone in premature calves.  |  Corum, O., et al. 2019. J Vet Pharmacol Ther. 42: 632-639. PMID: 31197850
  7. Pharmacokinetic and pharmacodynamic integration for optimal dosage of cefquinome against Streptococcus equi subsp. equi in foals.  |  Lee, DH., et al. 2020. Vet Res. 51: 131. PMID: 33059768
  8. Determination of Susceptibility Breakpoint for Cefquinome against Streptococcus suis in Pigs.  |  Mi, K., et al. 2021. Antibiotics (Basel). 10: PMID: 34439008
  9. PK/PD integration and pharmacodynamic cutoff of cefquinome against cow mastitis due to Escherichia coli.  |  Xiao, X., et al. 2022. J Vet Pharmacol Ther. 45: 83-91. PMID: 34469000
  10. RNA-seq-based transcriptome analysis of a cefquinome-treated, highly resistant, and virulent MRSA strain.  |  Iqbal, Z., et al. 2021. Microb Pathog. 160: 105201. PMID: 34547409
  11. Intestinal Exposure to Ceftiofur and Cefquinome after Intramuscular Treatment and the Impact of Ceftiofur on the Pig Fecal Microbiome and Resistome.  |  Rutjens, S., et al. 2022. Antibiotics (Basel). 11: PMID: 35326805
  12. Evaluation of cefquinome's efficacy in controlling avian colibacillosis and detection of its residues using high performance liquid chromatography (HPLC).  |  El-Tahawy, AO., et al. 2022. Saudi J Biol Sci. 29: 3502-3510. PMID: 35844377
  13. Pharmacokinetics of cefquinome in rainbow trout (Oncorhynchus mykiss) after intravascular, intraperitoneal, and oral administrations.  |  Durna Corum, D., et al. 2022. J Vet Pharmacol Ther. 45: 578-583. PMID: 36000461
  14. The pharmacokinetics and pharmacodynamics of cefquinome against Streptococcus agalactiae in a murine mastitis model.  |  Yang, Q., et al. 2023. PLoS One. 18: e0278306. PMID: 36696421

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cefquinome, 100 mg

sc-357308
100 mg
$82.00

Cefquinome, 250 mg

sc-357308A
250 mg
$291.00