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Cefpirome sulfate (CAS 98753-19-6)

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Alternate Names:
1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-6,7-dihydro-5H-cyclopenta[b]pyrindinium Inner Salt
Application:
Cefpirome sulfate is a fourth generation cephalosporin antibiotic
CAS Number:
98753-19-6
Purity:
≥98%
Molecular Weight:
612.67
Molecular Formula:
C22H22N6O5S2•H2SO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cefpirome Sulfate is a compound investigated in the context of its bactericidal properties, particularly its efficacy against Gram-positive and Gram-negative bacteria. In microbiological research, it is used to understand the dynamics of bacterial resistance mechanisms and the effectiveness of various antibiotics in different bacterial strains. Studies involving Cefpirome Sulfate often focus on its mechanism of action, which involves binding to penicillin-binding proteins and disrupting cell wall synthesis, leading to bacterial cell death. This chemical is also a subject of interest in environmental science, where research is conducted to analyze its degradation and the potential impact on microbial communities in wastewater treatment systems. Additionally, Cefpirome Sulfate serves as a reference compound in analytical chemistry for developing new detection methods in complex matrices, such as biological fluids or environmental samples.


Cefpirome sulfate (CAS 98753-19-6) References

  1. Toxicity of cefpirome: an overview.  |  Donaubauer, HH. and Mayer, D. 1992. J Antimicrob Chemother. 29 Suppl A: 71-3. PMID: 1601761
  2. [Antigenicity study of cefpirome sulfate].  |  Inoue, S., et al. 1990. J Toxicol Sci. 15 Suppl 3: 129-45. PMID: 2074601
  3. [Fertility study of cefpirome sulfate in rats].  |  Sugiyama, O., et al. 1990. J Toxicol Sci. 15 Suppl 3: 53-64. PMID: 2074604
  4. [Teratological study of cefpirome sulfate in rats].  |  Sugiyama, O., et al. 1990. J Toxicol Sci. 15 Suppl 3: 65-89. PMID: 2074605
  5. Stability studies of cefpirome sulfate in the solid state: Identification of degradation products.  |  Zalewski, P., et al. 2014. J Pharm Biomed Anal. 92: 22-5. PMID: 24469097
  6. Development and validation of stability-indicating HPLC method for determination of cefpirome sulfate.  |  Zalewski, P., et al. 2014. Acta Pol Pharm. 71: 731-6. PMID: 25362801
  7. Investigation on the interaction of cefpirome sulfate with lysozyme by fluorescence quenching spectroscopy and synchronous fluorescence spectroscopy.  |  Han, R., et al. 2016. Luminescence. 31: 580-586. PMID: 26304690
  8. The radiolytic studies of cefpirome sulfate in the solid state.  |  Zalewski, P., et al. 2016. J Pharm Biomed Anal. 118: 410-416. PMID: 26597316
  9. STABILITY OF CEFPIROME SULFATE IN AQUEOUS SOLUTIONS.  |  Zalewski, P., et al. 2016. Acta Pol Pharm. 73: 23-7. PMID: 27008797
  10. Antibiotic Prophylaxis Using Cefpirome Sulfate in Gynecologic Surgery and Elimination Rate of Enterococcus faecalis from the Vagina.  |  Kubota, T. and Utsuono, S. 1996. J Infect Chemother. 1: 197-200. PMID: 29681364
  11. Separation and characterization of impurities and isomers in cefpirome sulfate by liquid chromatography/tandem mass spectrometry and a summary of the fragmentation pathways of oxime-type cephalosporins.  |  Ren, X., et al. 2021. Rapid Commun Mass Spectrom. 35: e9004. PMID: 33188542
  12. Stability of cefpirome sulfate in the presence of commonly used intensive care drugs during simulated Y-site injection.  |  Allen, LV., et al. 1995. Am J Health Syst Pharm. 52: 2427-33. PMID: 8564608
  13. Cefpirome. A review of its antibacterial activity, pharmacokinetic properties and clinical efficacy in the treatment of severe nosocomial infections and febrile neutropenia.  |  Wiseman, LR. and Lamb, HM. 1997. Drugs. 54: 117-40. PMID: 9211085

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cefpirome sulfate, 1 g

sc-217860
1 g
$228.00