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Cefoxitin sodium salt (CAS 33564-30-6)

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Alternate Names:
Cefoxitin sodium salt also known as (6R,7S)-3-[[(Aminocarbonyl)oxy]methyl]-7-methoxy-8-oxo-7-[(2-thienylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Sodium Salt; Betacef; Cefaxilin Sodium
Application:
Cefoxitin sodium salt is a semi-synthetic antibiotic derived from Cephamycin C and possesses a high resistance to Beta lactamase inactivation
CAS Number:
33564-30-6
Purity:
≥95%
Molecular Weight:
449.43
Molecular Formula:
C16H16N3O7S2•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cefoxitin Sodium Salt is a substance that is primarily used in research to examine the efficacy and mechanism of action against bacteria, particularly those that are Gram-negative and resistant to certain other antibiotics. In microbiology studies, Cefoxitin Sodium Salt is often used as a benchmark to determine the susceptibility of bacterial strains to beta-lactam antibiotics. It is also employed in the study of beta-lactamase enzymes that bacteria produce to confer resistance against beta-lactam antibiotics. By understanding how Cefoxitin Sodium Salt is deactivated by these enzymes, researchers can develop strategies to inhibit this resistance mechanism. Furthermore, in the field of bacterial genetics, it is used to investigate the genes responsible for antibiotic resistance and the conditions that lead to their expression.


Cefoxitin sodium salt (CAS 33564-30-6) References

  1. Predicting the genotoxicity of thiophene derivatives from molecular structure.  |  Mosier, PD., et al. 2003. Chem Res Toxicol. 16: 721-32. PMID: 12807355
  2. Classification structure-activity relationship (CSAR) studies for prediction of genotoxicity of thiophene derivatives.  |  Du, H., et al. 2008. Toxicol Lett. 177: 10-9. PMID: 18243595
  3. Targeted gene replacement in fungal pathogens via Agrobacterium tumefaciens- mediated transformation.  |  Frandsen, RJ., et al. 2012. Methods Mol Biol. 835: 17-45. PMID: 22183645
  4. Improvement of the evaluation method for teratogenicity using zebrafish embryos.  |  Yamashita, A., et al. 2014. J Toxicol Sci. 39: 453-64. PMID: 24849680
  5. Investigation on the effect of fluorescence quenching of bovine serum albumin by cefoxitin sodium using fluorescence spectroscopy and synchronous fluorescence spectroscopy.  |  Li, G., et al. 2016. Luminescence. 31: 1054-62. PMID: 26678839
  6. Cefoxitin sodium activity against anaerobes: effect of the inoculum size, pH variation and different culture media.  |  Perea, EJ., et al. 1978. J Antimicrob Chemother. 4: 55-60. PMID: 29027
  7. Large-Scale Analysis of the Mycoplasma bovis Genome Identified Non-essential, Adhesion- and Virulence-Related Genes.  |  Josi, C., et al. 2019. Front Microbiol. 10: 2085. PMID: 31572317
  8. A new vector system for targeted integration and overexpression of genes in the crop pathogen Fusarium solani.  |  Nielsen, MR., et al. 2019. Fungal Biol Biotechnol. 6: 25. PMID: 31890232
  9. Antibacterial Activity of Lactobacillus Strains Isolated from Mongolian Yogurt against Gardnerella vaginalis.  |  Qian, Z., et al. 2020. Biomed Res Int. 2020: 3548618. PMID: 32382546
  10. Pre-validation of choriogenin H transgenic medaka eleutheroembryos as a quantitative estrogenic activity test method.  |  Chen, X., et al. 2021. Anal Biochem. 629: 114311. PMID: 34302800
  11. Variable importance for projection (VIP) scores for analyzing the contribution of risk factors in severe adverse events to Xiyanping injection.  |  Zheng, R., et al. 2023. Chin Med. 18: 15. PMID: 36782216
  12. Efficacy of Omadacycline-Containing Regimen in a Mouse Model of Pulmonary Mycobacteroides abscessus Disease.  |  Rimal, B., et al. 2023. mSphere. e0066522. PMID: 36912629
  13. Stability of clindamycin phosphate and ceftizoxime sodium, cefoxitin sodium, cefamandole nafate, or cefazolin sodium in two intravenous solutions.  |  Bosso, JA. and Townsend, RJ. 1985. Am J Hosp Pharm. 42: 2211-4. PMID: 3864367
  14. Cefoxitin, a semisynthetic cephamycin antibiotic: susceptibility studies.  |  Wallick, H. and Hendlin, D. 1974. Antimicrob Agents Chemother. 5: 25-32. PMID: 4840447

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cefoxitin sodium salt, 1 g

sc-217858
1 g
$189.00

Do you any specific values for solubility?

Asked by: SCchem16
Thank you for your question. This chemical, Cefoxitin sodium salt (CAS 33564-30-6), is soluble in water at 50mg/ml.
Answered by: Chemical Support 2
Date published: 2018-11-13
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Rated 5 out of 5 by from Various publications cite the use of CefoxitinVarious publications cite the use of Cefoxitin sodium salt, a semi-synthetic antibiotic, for MRSA surveillance cultures. -SCBT Publication Review
Date published: 2015-03-16
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Cefoxitin sodium salt is rated 5.0 out of 5 by 1.
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