Molecular structure of Cefotaxime sodium salt, CAS Number: 64485-93-4
Cefotaxime sodium salt (CAS 64485-93-4)
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Alternate Names:
Cefotaxime sodium salt is also known as Sym-methoxyimino Cephalosporin.
Application:
Cefotaxime sodium salt is a third generation β-lactamase resistant antibiotic with efficacy in prohibition of gram-positive and gram-negative bacterial cell wall synthesis.
CAS Number:
64485-93-4
Purity:
95%
Molecular Weight:
477.45
Molecular Formula:
C16H16N5O7S2•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Cefotaxime sodium salt is a third generation Cephalosporin β-lactamase resistant antibiotic with efficacy in prohibition of gram-positive and gram-negative bacterial cell wall synthesis. Cefotaxime sodium salt has demonstrated greater activity than other available first- and second-generation cephalosporins against Enterobacteriaceae. Cefotaxime sodium salt is more active than older cephalosporins against Pseudomonas aeruginosa and Acinetobacter spp., but most strains are still considered resistant. Cefotaxime sodium salt is also active against some gram-negative bacilli that are resistant to aminoglycosides, including amikacin (sc-278692). The activity of Cefotaxime sodium salt is comparable with other cephalosporins against gram-positive cocci, except staphylococci and enterococci, which are resistant. In combination with penicillins or aminoglycosides, Cefotaxime sodium salt may be synergistic against selected gram-negative bacilli.
Cefotaxime sodium salt (CAS 64485-93-4) References
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- Synergistic antibacterial interaction of cefotaxime and desacetylcefotaxime. | Molinari, G., et al. 1991. J Chemother. 3: 6-12. PMID: 2019866
- Human serum paraoxonase-1 (hPON1): in vitro inhibition effects of moxifloxacin hydrochloride, levofloxacin hemihidrate, cefepime hydrochloride, cefotaxime sodium and ceftizoxime sodium. | Türkeş, C., et al. 2015. J Enzyme Inhib Med Chem. 30: 622-8. PMID: 25519764
- Relationship between the color stability and impurity profile of cefotaxime sodium. | Sun, H., et al. 2017. J Chromatogr B Analyt Technol Biomed Life Sci. 1063: 235-244. PMID: 28890363
- Effect of Moisture Content of Chitin-Calcium Silicate on Rate of Degradation of Cefotaxime Sodium. | Al-Nimry, SS. and Alkhamis, KA. 2018. AAPS PharmSciTech. 19: 1337-1343. PMID: 29340979
- The relationship between the Hammett acidity and the decomposition of cefotaxime sodium in the solid state. | Altaani, BM., et al. 2020. Drug Dev Ind Pharm. 46: 1632-1638. PMID: 32838573
- Decomposition process of cefotaxime sodium from antibiotic wastewater by Up-flow Blanket Filter (UBF) reactor: Reactor performance, sludge characteristics and microbial community structure analysis. | Wang, J., et al. 2021. Sci Total Environ. 758: 143670. PMID: 33257062
- Exploiting of Green Synthesized Metal Oxide Nanoparticles for Spectrophotometric Determination of Levofloxacin, Cephalexin, and Cefotaxime Sodium in Commercial Products. | Alarfaj, NA., et al. 2021. Nanomaterials (Basel). 11: PMID: 33923143
- Efficacy of Etimicin Sulfate Combined with Cefotaxime Sodium in the Treatment of Patients with Septic Shock and Effect on Serum Inflammatory Factor Levels and Immune Function. | Pang, S., et al. 2021. Evid Based Complement Alternat Med. 2021: 8583118. PMID: 34527067
- Study of the polymerized impurities in cefotaxime sodium and cefepime by applying various chromatographic modes coupled with ion trap/time-of-flight mass spectrometry. | Ren, X., et al. 2022. Talanta. 238: 123079. PMID: 34808572
- Cefotaxime Mediated Synthesis of Gold Nanoparticles: Characterization and Antibacterial Activity. | Al Hagbani, T., et al. 2022. Polymers (Basel). 14: PMID: 35215685
- Electrocatalytic oxidation of low concentration cefotaxime sodium wastewater using Ti/SnO2-RuO2 electrode: Feasibility analysis and degradation mechanism. | Niu, Y., et al. 2022. Chemosphere. 297: 134146. PMID: 35231478
- Design of Cefotaxime Sodium-Loaded Polydopamine Coatings with Controlled Surface Roughness for Titanium Implants. | He, F., et al. 2022. ACS Biomater Sci Eng. 8: 4751-4763. PMID: 36191062
- Histological Changes in Ovary Treated with Dexamethasone and Cefotaxime Sodium. | Omairi, S., et al. 2022. Arch Razi Inst. 77: 999-1005. PMID: 36618313
- Cefotaxime: microbiology, pharmacology, and clinical use. | Dudley, MN. and Barriere, SL. 1982. Clin Pharm. 1: 114-24. PMID: 6309465
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cefotaxime sodium salt, 250 mg | sc-202989 | 250 mg | $30.00 | |||
Cefotaxime sodium salt, 1 g | sc-202989A | 1 g | $42.00 | |||
Cefotaxime sodium salt, 5 g | sc-202989B | 5 g | $66.00 | |||
Cefotaxime sodium salt, 10 g | sc-202989C | 10 g | $112.00 | |||
Cefotaxime sodium salt, 25 g | sc-202989D | 25 g | $132.00 | |||
Cefotaxime sodium salt, 100 g | sc-202989E | 100 g | $285.00 |