Cefoperazone acid (CAS 62893-19-0)

Cefoperazone Acid, a broad-spectrum, third-generation cephalosporin, is a semisynthetic compound known for its antibacterial activity. By binding to penicillin-binding proteins (PBPs) situated on the inner membrane of bacterial cells, Cefoperazone Acid effectively renders them inactive. PBPs play a role in the final stages of constructing the bacterial cell wall and reshaping it during growth and division. Through the inactivation of PBPs, the essential cross-linkage of peptidoglycan chains necessary for the strength and rigidity of the bacterial cell wall is disrupted. Consequently, the integrity of the bacterial cell wall weakens, leading to cell lysis and destruction. This antibacterial mechanism highlights Cefoperazone Acid′s efficacy against a broad range of bacterial infections. Moreover, cefoperazone Acid, a related compound, exhibits potent inhibitory properties against LACTB (β-lactamase), an enzyme responsible for antibiotic resistance. This additional feature enhances Cefoperazone Acid′s antimicrobial activity by countering the mechanisms employed by certain bacteria to evade β-lactam antibiotics.