Date published: 2025-12-17

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Cefditoren Pivaloyloxymethyl Ester (CAS 117467-28-4)

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Alternate Names:
Cefditoren Pivoxil
Application:
Cefditoren Pivaloyloxymethyl Ester is a third generation cephalosporin and β-Lactam antibacterial
CAS Number:
117467-28-4
Molecular Weight:
620.72
Molecular Formula:
C25H28N6O7S3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cefditoren Pivaloyloxymethyl Ester is a third generation cephalosporin and beta-Lactam antibacterial effective against a wide range of both Gram-positive and Gram-negative bacteria. It is a highly potent and selective inhibitor of bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs), which disrupts the formation of peptidoglycan, an essential component of the bacterial cell wall. This prevents the bacteria from forming new cell walls and ultimately leads to cell death. It has also been shown to inhibit the production of toxins and other compounds that are produced by bacteria. Lastly, Cefditoren Pivaloyloxymethyl Ester has been employed to study its effects on inflammation, cell viability, apoptosis, and cell cycle regulation.


Cefditoren Pivaloyloxymethyl Ester (CAS 117467-28-4) References

  1. Effect of fluoroquinolones on body temperature of mice.  |  Miyazaki, S., et al. 2008. J Antimicrob Chemother. 62: 1319-22. PMID: 18840887
  2. Development and validation of the stability-indicating LC-UV method for the determination of Cefditoren pivoxil.  |  Annapurna, MM., et al. 2012. J Pharm Anal. 2: 466-469. PMID: 29403785
  3. Visualizing ToF-SIMS Hyperspectral Imaging Data Using Color-Tagged Toroidal Self-Organizing Maps.  |  Gardner, W., et al. 2019. Anal Chem. 91: 13855-13865. PMID: 31549810
  4. A comparative performance evaluation of cephalosporin's drugs for fluoride recognition.  |  Kumar, SS., et al. 2023. Anal Sci. 39: 527-535. PMID: 36645644
  5. In vivo Pharmacokinetics/Pharmacodynamics Profiles for Appropriate Doses of Cefditoren pivoxil against S. pneumoniae in Murine Lung-Infection Model.  |  Igarashi, Y., et al. 2023. Pharm Res. 40: 1789-1797. PMID: 37253866
  6. Mutagenicity study of the new cephalosporin antibiotic cefditoren pivoxil.  |  Shindo, Y., et al. 1996. Arzneimittelforschung. 46: 815-21. PMID: 9125285
  7. RP-HPLC methods for the determination of cephalosporins (Cefditoren Pivoxil and Cefdinir) in pharmaceutical dosage forms.  |  Narala, et al. 2011. Journal of Pharmaceutical Sciences and Research. 3.1: 1002.
  8. Different validated methods for determination of cefditoren pivoxil.  |  El-Bagary, et al. 2013. JPC–Journal of Planar Chromatography–Modern TLC. 26: 43-55.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cefditoren Pivaloyloxymethyl Ester, 10 mg

sc-211039
10 mg
$209.00