Date published: 2025-12-5

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Cefcapene Pivoxil Hydrochloride (CAS 147816-23-7)

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Alternate Names:
(6R,7R)-3-[[(Aminocarbonyl)oxy]methyl]-7-[[(2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid
Application:
Cefcapene Pivoxil Hydrochloride is antibacterial agent with Gram-(+)/(−) activity
CAS Number:
147816-23-7
Molecular Weight:
604.10
Molecular Formula:
C23H30ClN5O8S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cefcapene pivoxil hydrochloride is a cephalosporin antibiotic derivative that has garnered attention in scientific research for its potent antibacterial properties and unique chemical structure. Its mechanism of action involves inhibiting bacterial cell wall synthesis by binding to penicillin-binding proteins, thereby disrupting peptidoglycan cross-linking and leading to bacterial cell lysis. In research settings, cefcapene pivoxil hydrochloride has been extensively studied for its efficacy against various bacterial pathogens, including Gram-positive and Gram-negative bacteria. Its broad-spectrum activity makes it a studying antibiotic synergy, valuable tool for investigating bacterial resistance mechanisms, and developing novel strategies. Furthermore, research has explored its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion, to optimize dosing regimens and enhance efficacy. Additionally, cefcapene pivoxil hydrochloride′s stability and compatibility with different formulations have facilitated its use in microbiology research, antimicrobial susceptibility testing, and pharmacological studies. Ongoing research efforts continue to explain its mode of action, evaluate its effectiveness against emerging bacterial strains, and explore potential applications in combating antibiotic-resistant infections and improving public health outcomes.


Cefcapene Pivoxil Hydrochloride (CAS 147816-23-7) References

  1. Drug eruption induced by cefcapene pivoxil hydrochloride.  |  Kawada, A., et al. 2001. Contact Dermatitis. 44: 197. PMID: 11218007
  2. Study of the absorption of cefcapene pivoxil in patients with infectious disease and soft stool or diarrhea.  |  Tanimura, H., et al. 2003. J Infect Chemother. 9: 75-82. PMID: 12673412
  3. In vitro activity and susceptibility to hydrolysis of S-1006.  |  Neu, HC., et al. 1992. Antimicrob Agents Chemother. 36: 1336-41. PMID: 1416835
  4. Absorption of ester prodrugs in Caco-2 and rat intestine models.  |  He, X., et al. 2004. Antimicrob Agents Chemother. 48: 2604-9. PMID: 15215116
  5. High-level expression, purification, and some properties of a recombinant cephalosporin-C deacetylase.  |  Takimoto, A., et al. 1999. J Biosci Bioeng. 87: 456-62. PMID: 16232499
  6. Clinical study of complicated urinary tract infection using 'The UTI Criteria (Draft Fourth Edition)': measurement methods for pyuria.  |  Arakawa, S., et al. 2006. Int J Urol. 13: 1484-7. PMID: 17118022
  7. Efficacy of azithromycin administration in prevention of respiratory tract infection after bronchoscopic biopsy: a randomized, controlled trial.  |  Kanazawa, H. 2007. Respirology. 12: 70-5. PMID: 17207028
  8. Successful neuroendoscopic treatment of intraventricular brain abscess rupture.  |  Nishizaki, T., et al. 2011. Clin Pract. 1: e52. PMID: 24765313
  9. Cefcapene Pivoxil Hydrochloride Is a Potentially New Treatment for Palmoplantar Pustulosis with Pustulotic Arthro-Osteitis.  |  Murakami, M., et al. 2015. Dermatology. 231: 304-11. PMID: 26440444
  10. Synthesis and structure-activity relationships of 7 beta-[(Z)-2-(2- aminothiazol-4-yl)-3-(substituted)-2-propenoylamino]-3-cephems with C-3 substitutions.  |  Ishikura, K., et al. 1994. J Antibiot (Tokyo). 47: 466-76. PMID: 8195047

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cefcapene Pivoxil Hydrochloride, 5 mg

sc-211038A
5 mg
$240.00

Cefcapene Pivoxil Hydrochloride, 10 mg

sc-211038
10 mg
$360.00

Cefcapene Pivoxil Hydrochloride, 25 mg

sc-211038B
25 mg
$690.00

Cefcapene Pivoxil Hydrochloride, 50 mg

sc-211038C
50 mg
$1240.00

Cefcapene Pivoxil Hydrochloride, 100 mg

sc-211038D
100 mg
$2290.00