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Cefcapene Pivoxil Hydrochloride is an antibacterial agent that has demonstrated activity against both gram-positive and gram-negative bacteria. The compound has documented antibacterial activity at 90% in vitro inhibition of Staphylococcus aureus A, B, C, F, and G streptococci and Streptococcus pneumoniae isolates at a concentration of less than or equal to 2μg/ml and 0.12μg/ml respectively. In the same study 100% of the isolates of Haemophilus influenzae were inhibited at concentrations equal to or less than 0.06μg/ml.
1. Neu, H.C., et al. 1992. Antimicrob. Agents Chemother. 36: 1336-1341. PMID: 1416835
2. Ishikura, K., et al. 1994. J. Antibiot. 47: 466-476. PMID: 8195047
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