Molecular structure of Cefamandole nafate, CAS Number: 42540-40-9
Cefamandole nafate (CAS 42540-40-9)
Alternate Names:
Cefamandole formate sodium salt
Application:
Cefamandole nafate is a compound used to study the effects of expression and inhibition of PBP 2A
CAS Number:
42540-40-9
Molecular Weight:
512.49
Molecular Formula:
C19H17N6O6S2Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Cefamandole nafate is used to study the effects of expression and inhibition of PBP 2A and other penicillin-binding proteins (PDPs) on bacterial cell wall mucopeptide synthesis. Cefamandole nafate is a powerful antibiotic belonging to the semi-synthetic cephalosporin class, known for its wide range of effectiveness. It shares a similar structure with cefazolin but possesses an extra N-methylthioacetamidomethyl side chain.
Cefamandole nafate (CAS 42540-40-9) References
- Synergistic activity of dispersin B and cefamandole nafate in inhibition of staphylococcal biofilm growth on polyurethanes. | Donelli, G., et al. 2007. Antimicrob Agents Chemother. 51: 2733-40. PMID: 17548491
- Antibiotic delivery polyurethanes containing albumin and polyallylamine nanoparticles. | Crisante, F., et al. 2009. Eur J Pharm Sci. 36: 555-64. PMID: 19136061
- Simultaneous determination of cefamandole and cefamandole nafate in human plasma and urine by high-performance liquid chromatography with column switching. | Lee, HS., et al. 1990. J Chromatogr. 528: 425-33. PMID: 2384580
- Efficacy and safety of cefamandole plus either gentamicin or tobramycin in therapy of severe gram-negative bacterial infections. | Gentry, LO. 1978. J Infect Dis. 137 Suppl: S144-S149. PMID: 349093
- Impurity profile and spectrum characteristics of the isomers in cefamandole nafate using high- performance liquid chromatography/high-performance size exclusion chromatography tandem ion trap/time-of-flight mass spectrometry. | Wang, F., et al. 2022. Rapid Commun Mass Spectrom. 36: e9399. PMID: 36114650
- Stability of clindamycin phosphate and ceftizoxime sodium, cefoxitin sodium, cefamandole nafate, or cefazolin sodium in two intravenous solutions. | Bosso, JA. and Townsend, RJ. 1985. Am J Hosp Pharm. 42: 2211-4. PMID: 3864367
- Chemical stabilities of cefamandole nafate and metronidazole when mixed together for intravenous infusion. | Das Gupta, V., et al. 1985. J Clin Hosp Pharm. 10: 379-83. PMID: 4093509
- Effect of cefamandole nafate on blood coagulation and platelet function. | Custer, GM., et al. 1979. Antimicrob Agents Chemother. 16: 869-72. PMID: 533268
- Toxicologic evaluation of cefamandole nafate in laboratory animals. | Wold, JS., et al. 1978. J Infect Dis. 137 Suppl: S51-S59. PMID: 650004
- Stability of cefamandole nafate and cefoxitin sodium solutions. | Das Gupta, V. and Stewart, KR. 1981. Am J Hosp Pharm. 38: 875-9. PMID: 7246563
- Formylation of glucose by cefamandole nafate at alkaline pH. | Indelicato, JM., et al. 1980. J Pharm Sci. 69: 1183-8. PMID: 7420288
- Effect of cefamandole nafate on the toxicity of tobramycin. | Wold, JS., et al. 1977. Antimicrob Agents Chemother. 12: 465-9. PMID: 921240
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cefamandole nafate, 5 g | sc-255012 | 5 g | $245.00 |