Molecular structure of Cefaclor, CAS Number: 53994-73-3
Cefaclor (CAS 53994-73-3)
Alternate Names:
7-(D-2-Amino-2-phenylacetamido)-3-chloro-3-cephem-4-carboxylic acid
Application:
Cefaclor is an antibiotic that inhibits cell wall synthesis
CAS Number:
53994-73-3
Purity:
>97%
Molecular Weight:
367.8
Molecular Formula:
C15H14ClN3O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Cefaclor is a cephalosporin antibiotic that inhibits cell wall synthesis. The antibiotic is active against a wide spectrum of common pathogens, including gram-positive and gram-negative bacteria. Cefaclor has been a subject of research in studies concerning bacterial resistance to antibiotics and the mechanisms of action of antibiotics.
Cefaclor (CAS 53994-73-3) References
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- Cefaclor revisited. | Meyers, BR. 2000. Clin Ther. 22: 154-66. PMID: 10743978
- Immunomodulatory properties of cefaclor: in vivo effect on cytokine release and lymphoproliferative response in rats. | Mangano, K., et al. 2006. J Chemother. 18: 641-7. PMID: 17267343
- Intestinal mucosal permeability of children with cefaclor-associated serum sickness-like reactions. | Zhang, Z., et al. 2013. Eur J Pediatr. 172: 537-43. PMID: 23296953
- Determination of cefaclor by UPLC-MS-MS for a Chinese pharmacokinetic study. | Huang, C., et al. 2014. J Chromatogr Sci. 52: 636-40. PMID: 23839802
- Covalent inhibition of New Delhi metallo-β-lactamase-1 (NDM-1) by cefaclor. | Thomas, PW., et al. 2014. Chembiochem. 15: 2541-8. PMID: 25302694
- Proper Cut-off Levels of Serum Specific IgE to Cefaclor for Patients with Cefaclor Allergy. | Nam, YH., et al. 2018. Yonsei Med J. 59: 968-974. PMID: 30187704
- Chromatographic studies of unusual on-column degradation of cefaclor observed in the impurity separation by HPLC. | Zhong, JS., et al. 2019. J Pharm Biomed Anal. 176: 112818. PMID: 31446297
- Integrative strategy to determine residual proteins in cefaclor produced by immobilized penicillin G acylase. | Wang, Y., et al. 2020. J Pharm Biomed Anal. 185: 113229. PMID: 32163852
- HPLC/ESI-MS identification of diastereomers of Impurity E - Degradation products of cefaclor. | Chuchracka, K., et al. 2020. J Pharm Biomed Anal. 190: 113533. PMID: 32814261
- Impact of cefaclor on the normal human oropharyngeal and intestinal microflora. | Nord, CE., et al. 1987. Scand J Infect Dis. 19: 681-5. PMID: 3441750
- Cefaclor: summary of clinical experience. | Kammer, RB. and Short, LJ. 1979. Infection. 7 Suppl 6: 631-5. PMID: 551092
- Pharmacokinetics of cefaclor in renal failure: effects of multiple doses and hemodialysis. | Spyker, DA., et al. 1982. Antimicrob Agents Chemother. 21: 278-81. PMID: 7073265
- Cefaclor concentration in pus from abscess caused by odontogenic infection after a single oral administration. | Akimoto, Y., et al. 1996. Gen Pharmacol. 27: 177-9. PMID: 8742518
- Cefaclor: a contemporary look at susceptibility of key pathogens from around the globe. | Preston, DA. and Turik, M. 1998. J Chemother. 10: 195-202. PMID: 9669643
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cefaclor, 10 mg | sc-202532 | 10 mg | $36.00 | |||
Cefaclor, 50 mg | sc-202532A | 50 mg | $51.00 | |||
Cefaclor, 250 mg | sc-202532B | 250 mg | $179.00 |