
Cdk2 Antibody (AN4.3) is a mouse monoclonal IgG2a kappa light chain antibody designed to detect Cyclin-dependent kinase 2 (Cdk2). anti-Cdk2 antibody (AN4.3) is raised against human recombinant Cdk2 and effectively recognizes Cdk2 from mouse, rat, and human species in western blotting (WB) and immunoprecipitation (IP) applications. Cdk2 is predominantly located in the nucleus of the cell, where it plays a crucial role in regulating the cell cycle by forming complexes with cyclins E and A. These complexes are essential for the transition from the G1 phase to the S phase and for the progression through the S phase, ensuring accurate DNA replication and cell division. The nuclear localization of Cdk2 is vital for maintaining genomic stability and controlling cell proliferation, making Cdk2 a key focus in cancer research and the development of therapeutic interventions. Additionally, Cdk2 interacts with other regulatory kinases such as Cdk3, Cdk8, PCTAIRE-1-3, and KKIALRE, underscoring Cdk2′s integral role in the complex network of cell cycle regulation. By enabling the detection and study of Cdk2, Cdk2 (AN4.3) antibody supports research into cell cycle dynamics, tumorigenesis, and the mechanisms underlying uncontrolled cell growth. Cdk2 monoclonal antibody (AN4.3) is an essential tool for scientists investigating the molecular pathways that govern cell growth and division, facilitating advancements in our understanding of cellular processes and disease mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cdk2 Antibody (AN4.3) | sc-53220 | 200 µg/ml | $322.00 |