Date published: 2026-4-5

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Cdk2 Antibody (AN4.3): sc-53220

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Datasheets
  • Cdk2 Antibody (AN4.3) is a mouse monoclonal IgG2a κ, cited in 10 publications, provided at 200 µg/ml
  • raised against human recombinant Cdk2
  • recommended for detection of Cdk2 of mouse, rat and human origin by WB and IP
  • See Cdk2 (D-12): sc-6248 for Cdk2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Cdk2 Antibody (AN4.3). This work is in progress.
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Cdk2 Antibody (AN4.3) is a mouse monoclonal IgG2a kappa light chain antibody designed to detect Cyclin-dependent kinase 2 (Cdk2). anti-Cdk2 antibody (AN4.3) is raised against human recombinant Cdk2 and effectively recognizes Cdk2 from mouse, rat, and human species in western blotting (WB) and immunoprecipitation (IP) applications. Cdk2 is predominantly located in the nucleus of the cell, where it plays a crucial role in regulating the cell cycle by forming complexes with cyclins E and A. These complexes are essential for the transition from the G1 phase to the S phase and for the progression through the S phase, ensuring accurate DNA replication and cell division. The nuclear localization of Cdk2 is vital for maintaining genomic stability and controlling cell proliferation, making Cdk2 a key focus in cancer research and the development of therapeutic interventions. Additionally, Cdk2 interacts with other regulatory kinases such as Cdk3, Cdk8, PCTAIRE-1-3, and KKIALRE, underscoring Cdk2′s integral role in the complex network of cell cycle regulation. By enabling the detection and study of Cdk2, Cdk2 (AN4.3) antibody supports research into cell cycle dynamics, tumorigenesis, and the mechanisms underlying uncontrolled cell growth. Cdk2 monoclonal antibody (AN4.3) is an essential tool for scientists investigating the molecular pathways that govern cell growth and division, facilitating advancements in our understanding of cellular processes and disease mechanisms.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cdk2 Antibody (AN4.3)

sc-53220
200 µg/ml
$322.00

For Western Blot, is it recommended to use denatured or non-denatured conditions with Cdk2 (AN4.3): sc-53220 monoclonal antibody?

Asked by: AbPolly
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-02-27
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Rated 4 out of 5 by from Worked with transfected lysate by WBWorked with transfected lysate by WB -SCBT QC
Date published: 2015-04-13
Rated 5 out of 5 by from The antibody works well for Western blottingThe antibody works well for Western blotting detecting endogenous Cdk2 from A-431 cells. -SCBT QC
Date published: 2015-03-17
Rated 5 out of 5 by from Good specificity and signal strength in KGood specificity and signal strength in K-562, HeLa and NAMALWA whole cell lysates. -SCBT QC
Date published: 2014-05-18
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Cdk2 Antibody (AN4.3) is rated 4.7 out of 5 by 3.
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