Cdk2 Antibody (55): sc-136191
- Cdk2 Antibody (55) is a mouse monoclonal IgG2a, cited in 6 publications, provided at 50 µg/0.5 ml
- raised against amino acids 109-298 of Cdk2 of human origin
- recommended for detection of Cdk2 of mouse, rat, human and canine origin by WB, IP and IF
- See Cdk2 (D-12): sc-6248 for Cdk2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Cdk2 Antibody (55). This work is in progress.
Cdk2 Antibody (55) is a mouse monoclonal IgG2a antibody engineered to detect Cyclin-dependent kinase 2 (Cdk2), also known as CDK2 or CDC2-like kinase 2 (CLK2). Anti-Cdk2 antibody (55) is raised against amino acids 109-298 of the human Cdk2 protein and effectively recognizes Cdk2 from mouse, rat, human, and canine species in western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF) applications. Cdk2 plays a fundamental role in cell cycle regulation by partnering with cyclins E and A to control the transition from the G1 phase to the S phase and the progression through the S phase, respectively. These interactions are critical for the initiation of DNA replication and the maintenance of genomic integrity, making Cdk2 essential for proper cell division and preventing uncontrolled cell proliferation. Dysregulation of Cdk2 activity is implicated in various cancers, highlighting Cdk2′s importance as a target for therapeutic intervention and cancer research. The ability of Cdk2 to form complexes with different cyclins allows for precise temporal control of kinase activity, ensuring that cells replicate DNA accurately and divide correctly. Additionally, Cdk2 interacts with other cyclin-dependent kinases, such as Cdk3, Cdk8, PCTAIRE-1-3, and KKIALRE, which underscores Cdk2′s integral role within the network of cell cycle regulators. Cdk2 monoclonal antibody (55) is a valuable tool for scientists studying the molecular mechanisms of cell cycle progression, tumorigenesis, and the development of anti-cancer therapies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cdk2 Antibody (55) | sc-136191 | 50 µg/0.5 ml | $322.00 |