Cdc20 Antibody (41): sc-136024
- Cdc20 Antibody (41) is a mouse monoclonal IgG1, cited in 2 publications, provided at 50 µg/0.5 ml
- raised against amino acids 60-253 of Cdc20 of human origin
- recommended for detection of Cdc20 of human origin by WB, IP and IF
- See Cdc20 (E-7): sc-13162 for Cdc20 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Cdc20 Antibody (41). This work is in progress.
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SEE ALSO...
Cdc20 Antibody (41) is a mouse monoclonal IgG1 antibody that detects CDC20 in human samples through western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). CDC20 is a crucial regulatory protein that plays a significant role in the cell cycle, particularly in the transition from the G2 phase to mitosis. Anti-CDC20 antibody (41) functions as an activator of the anaphase-promoting complex/cyclosome (APC/C), which is essential for the degradation of specific proteins that regulate cell cycle progression. This degradation is vital for the proper timing of mitosis, ensuring that cells do not prematurely enter anaphase, which could lead to genomic instability and contribute to tumorigenesis. CDC20 is predominantly located in the cytoplasm during interphase and translocates to the nucleus as cells prepare for mitosis, highlighting its dynamic role in cell cycle regulation. CDC20 (41) monoclonal antibody is an invaluable tool for researchers studying cell cycle dynamics and the mechanisms underlying cell division, providing insights into potential therapeutic targets for cancer treatment.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cdc20 Antibody (41) | sc-136024 | 50 µg/0.5 ml | $322.00 |