CD98 Antibody (F-2): sc-390154

CD98 (F-2) is a mouse monoclonal IgM kappa antibody that detects CD98 of mouse, rat and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP) and enzyme-linked immunosorbent assay (ELISA). Anti-CD98 antibody (F-2) is available as the non-conjugated form. CD98 (4F2, CD98, MDU1, 4F2HC, 4T2HC, NACAE, SLC3A2) is a disulfide-linked heterodimer composed of a glycosylated heavy chain and a non-glycosylated light chain. CD98 is a scaffolding protein that interacts with basolaterally expressed amino acid transporters and β1 integrins and can alter amino acid transport and cell adhesion, migration and branching morphogenesis. The heavy chain is a type II integral membrane protein. CD98 is expressed on T cells and is upregulated upon T cell activation. CD98 is also present on monocytes and at lower levels on granulocytes, platelets and lymphocytes. Evidence suggests that CD98 may play a role in the regulation of T cell activation and proliferation. Alternate transcriptional splice variants, encoding different isoforms exist for the human CD98 gene.

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-CD98 Antibody (F-2) has 6 citations in a variety of scientific publications.

Primary antibodies like Anti-CD98 Antibody (F-2) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

CD98 Antibody (F-2) Specifications

Alternate Product Name: SLC3A2

Product Clone Name: F-2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgM kappa light chain

Amino Acids:

Epitope Target: CD98

Epitope Species: human

Product Reactivity/Detection: CD98

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: equine

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgM kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 6 citations in various scientific publications

Available Conjugates/Forms for CD98 Antibody (F-2): P: Blocking Peptide

The preferred CD98 antibody is CD98 Antibody (4F2): sc-59145.