CD98 Antibody (30): sc-136139
- CD98 Antibody (30) is a mouse monoclonal IgG1, cited in 1 publications, provided at 50 µg/0.5 ml
- raised against amino acids 9-204 of CD98 of rat origin
- recommended for detection of CD98 heavy chain (HC) and CD98 precursor of mouse and rat origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD98 Antibody (30). This work is in progress.
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CD98 Antibody (30) is a mouse monoclonal IgG1 antibody that detects CD98 in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-CD98 antibody (30) recognizes a disulfide-linked heterodimer composed of a glycosylated heavy chain and a non-glycosylated light chain, which plays a crucial role as a scaffolding protein that interacts with basolaterally expressed amino acid transporters and β1 integrins. CD98 (30) monoclonal antibody regulates amino acid transport, cell adhesion, migration, and branching morphogenesis, processes essential for various physiological functions, including immune responses and tissue development. The heavy chain of CD98 is classified as a type II integral membrane protein and is predominantly expressed on T cells, where CD98 (30) antibody shows upregulation upon T cell activation, indicating potential involvement in T cell activation and proliferation. CD98 monoclonal antibody (30) also detects expression on monocytes and at lower levels on granulocytes, platelets, and lymphocytes, highlighting importance in immune cell function. Alternate transcriptional splice variants exist for the human CD98 gene, encoding different isoforms that may have distinct roles in cellular processes, further emphasizing the complexity and significance of CD98 in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD98 Antibody (30) | sc-136139 | 50 µg/0.5 ml | $322.00 |