

CD94 Antibody (HP-3B1) is a mouse monoclonal IgG2a antibody that detects CD94 in human samples through applications such as immunofluorescence (IF) and flow cytometry (FCM). CD94 is a type II membrane glycoprotein that plays a crucial role in the immune response by forming heterodimers with NKG2 isoforms on the surface of natural killer (NK) cells. This interaction is vital for the regulation of NK cell activity, as CD94 helps to distinguish between healthy and stressed or infected cells. CD94 expression on NK cells allows for the recognition of stress-inducible ligands, such as MICA, which are often overexpressed in various epithelial tumors. By facilitating NK cell activation in response to these ligands, CD94 is essential for the immune system′s ability to target and eliminate malignant cells, making CD94 a significant focus of research in cancer immunotherapy. Anti-CD94 antibody (HP-3B1) serves as an invaluable tool for studying NK cell activation dynamics and immune surveillance mechanisms in human health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD94 Antibody (HP-3B1) | sc-59143 | 200 µg/ml | $322.00 |