CD94 Antibody (18D3) is a rat monoclonal IgG2a antibody that detects CD94 in mouse samples through flow cytometry (FCM). CD94 is a type II membrane glycoprotein that plays a crucial role in the immune response by forming heterodimers with NKG2 isoforms on the surface of natural killer (NK) cells. This interaction is vital for the recognition of stressed or infected cells, as CD94-NKG2 complexes are involved in the regulation of NK cell activity, enhancing their ability to target and eliminate abnormal cells, such as those found in tumors. The importance of CD94 in immune surveillance is underscored by CD94′s ability to interact with various ligands, including the stress-inducible protein MICA, which is often overexpressed in epithelial tumors. Anti-CD94 antibody (18D3) enables researchers to gain insights into the mechanisms of immune regulation and potential therapeutic targets for enhancing NK cell responses in cancer immunotherapy.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD94 Antibody (18D3) | sc-53016 | 200 µg/ml | $322.00 | |||
CD94 Antibody (18D3) FITC | sc-53016 FITC | 200 µg/ml | $336.00 | |||
CD94 Antibody (18D3) PE | sc-53016 PE | 200 µg/ml | $349.00 |