CD26 Antibody (BA5): sc-19607
- CD26 Antibody (BA5) is a mouse monoclonal IgG2a, cited in 6 publications, provided at 200 µg/ml
- raised against human thymic T lymphocyte clone
- recommended for detection of CD26 of human origin by IF and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD26 Antibody (BA5). This work is in progress.
QUICK LINKS
SEE ALSO...
CD26 Antibody (BA5) is a rat monoclonal IgG2a antibody that detects CD26 in human samples through immunofluorescence (IF) and flow cytometry (FCM) applications. CD26, also known as dipeptidylpeptidase 4, plays a crucial role in immune regulation, acting as a T cell activation molecule and a regulator of chemokine function. This membrane glycoprotein is primarily located on the surface of various immune cells, including T lymphocytes, where CD26 facilitates critical interactions within the immunological synapse. CD26 on lymphocytes allows for the colocalization of adenosine deaminase with adenosine receptors on dendritic cells, enhancing the costimulatory signals necessary for T cell activation. This interaction is vital for the production of proinflammatory cytokines such as interferon-gamma, tumor necrosis factor-alpha, and interleukin-6, which are essential for mounting an effective immune response. Furthermore, CD26′s involvement in the pathogenesis of human cancers, including both solid tumors and hematological malignancies, underscores its importance in cancer biology and potential as a therapeutic target. Anti-CD26 antibody (BA5) is an invaluable tool for researchers investigating the multifaceted roles of CD26 in immune responses and disease mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CD26 Antibody (BA5) References:
- Regulation and roles of CD26/DPPIV in hematopoiesis and diseases. | Aliyari Serej, Z., et al. 2017. Biomed Pharmacother. 91: 88-94. PMID: 28448874
- CD26 - The emerging role of a costimulatory molecule in allograft rejection. | Jungraithmayr, W. and Enz, N. 2020. Cell Mol Immunol. 17: 1208-1209. PMID: 29622798
- CD26/Dipeptidyl Peptidase IV and Its Multiple Biological Functions. | Pan, K., et al. 2021. Cureus. 13: e13495. PMID: 33777580
- Cellular expression of CD26/dipeptidyl peptidase IV. | Iwanaga, T. and Nio-Kobayashi, J. 2021. Biomed Res. 42: 229-237. PMID: 34937822
- CD26/DPP-4 in Chronic Myeloid Leukemia. | Sicuranza, A., et al. 2022. Cancers (Basel). 14: PMID: 35205639
- Therapeutic Perspectives of CD26 Inhibitors in Imune-Mediated Diseases. | Hu, X., et al. 2022. Molecules. 27: PMID: 35889373
- CD26 and Cancer. | Cordero, OJ. 2022. Cancers (Basel). 14: PMID: 36358613
- CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer. | Houthuijzen, JM., et al. 2023. Nat Commun. 14: 183. PMID: 36635273
- Functional roles of CD26/DPP4 in lipopolysaccharide-induced lung injury. | Sato, S., et al. 2024. Am J Physiol Lung Cell Mol Physiol. 326: L562-L573. PMID: 38469626
- Selective refueling of CAR T cells using ADA1 and CD26 boosts antitumor immunity. | Hu, Y., et al. 2024. Cell Rep Med. 5: 101530. PMID: 38688275
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD26 Antibody (BA5) | sc-19607 | 200 µg/ml | $316.00 | |||
CD26 Antibody (BA5) FITC | sc-19607 FITC | 200 µg/ml | $330.00 | |||
CD26 Antibody (BA5) PE | sc-19607 PE | 200 µg/ml | $343.00 |