CCZ1 Antibody (B-7): sc-514290
- CCZ1 Antibody (B-7) is a mouse monoclonal IgG1 κ CCZ1 antibody, cited in 11 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 244-269 within an internal region of CCZ1 of human origin
- CCZ1 Antibody (B-7) is recommended for detection of CCZ1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-CCZ1 Antibody (B-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CCZ1 Antibody (B-7) for WB applications. These reagents are now offered in bundles with CCZ1 Antibody (B-7) (see ordering information below).
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CCZ1 Antibody (B-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects CCZ1 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CCZ1 (B-7) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CCZ1, also known as CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae), CCZ1A, CCZ1B, or CGI-43, consists of 482 amino acids and is primarily localized to the lysosomal membrane, which is crucial for its role in cellular waste management and recycling processes. The lysosome is essential for degrading and recycling cellular components, and proper functioning of CCZ1 is vital for maintaining cellular homeostasis and preventing the accumulation of damaged organelles and proteins. CCZ1 is encoded by a gene located on human chromosome 7, a region associated with various genetic disorders, including osteogenesis imperfecta and Pendred syndrome, highlighting the importance of CCZ1 in both normal physiology and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CCZ1 Antibody (B-7) References:
- Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. | Lai, CH., et al. 2000. Genome Res. 10: 703-13. PMID: 10810093
- Long-term audiological feature in Pendred syndrome caused by PDS mutation. | Iwasaki, S., et al. 2001. Arch Otolaryngol Head Neck Surg. 127: 705-8. PMID: 11405873
- Williams-Beuren syndrome diagnosis using fluorescence in situ hybridization. | Osborne, LR., et al. 2006. Methods Mol Med. 126: 113-28. PMID: 16930009
- Lissencephaly 1 linking to multiple diseases: mental retardation, neurodegeneration, schizophrenia, male sterility, and more. | Reiner, O., et al. 2006. Neuromolecular Med. 8: 547-65. PMID: 17028375
- Therapy-related leukemia and myelodysplasia: susceptibility and incidence. | Leone, G., et al. 2007. Haematologica. 92: 1389-98. PMID: 17768113
- Integral and associated lysosomal membrane proteins. | Schröder, B., et al. 2007. Traffic. 8: 1676-1686. PMID: 17897319
- Mutants of the Saccharomyces cerevisiae VPS genes CCZ1 and YPT7 are blocked in different stages of sporulation. | Piekarska, I., et al. 2010. Eur J Cell Biol. 89: 780-7. PMID: 20709422
- Restriction fragment length polymorphism associated with the pro alpha 2(I) gene of human type I procollagen. Application to a family with an autosomal dominant form of osteogenesis imperfecta. | Tsipouras, P., et al. 1983. J Clin Invest. 72: 1262-7. PMID: 6313757
- Molecular anatomy of chromosome 7q deletions in myeloid neoplasms: evidence for multiple critical loci. | Liang, H., et al. 1998. Proc Natl Acad Sci U S A. 95: 3781-5. PMID: 9520444
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CCZ1 Antibody (B-7) | sc-514290 | 200 µg/ml | $322.00 | |||
CCZ1 Antibody (B-7): m-IgG Fc BP-HRP Bundle | sc-531081 | 200 µg Ab; 10 µg BP | $361.00 | |||
CCZ1 Antibody (B-7): m-IgGκ BP-HRP Bundle | sc-524675 | 200 µg Ab, 40 µg BP | $361.00 | |||
CCZ1 Antibody (B-7): m-IgG1 BP-HRP Bundle | sc-544387 | 200 µg Ab; 20 µg BP | $361.00 | |||
CCZ1 Antibody (B-7) AC | sc-514290 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CCZ1 Antibody (B-7) HRP | sc-514290 HRP | 200 µg/ml | $322.00 | |||
CCZ1 Antibody (B-7) FITC | sc-514290 FITC | 200 µg/ml | $336.00 | |||
CCZ1 Antibody (B-7) PE | sc-514290 PE | 200 µg/ml | $349.00 | |||
CCZ1 Antibody (B-7) Alexa Fluor® 488 | sc-514290 AF488 | 200 µg/ml | $364.00 | |||
CCZ1 Antibody (B-7) Alexa Fluor® 546 | sc-514290 AF546 | 200 µg/ml | $364.00 | |||
CCZ1 Antibody (B-7) Alexa Fluor® 594 | sc-514290 AF594 | 200 µg/ml | $364.00 | |||
CCZ1 Antibody (B-7) Alexa Fluor® 647 | sc-514290 AF647 | 200 µg/ml | $364.00 | |||
CCZ1 Antibody (B-7) Alexa Fluor® 680 | sc-514290 AF680 | 200 µg/ml | $364.00 | |||
CCZ1 Antibody (B-7) Alexa Fluor® 790 | sc-514290 AF790 | 200 µg/ml | $364.00 | |||
CCZ1 (B-7) Neutralizing Peptide | sc-514290 P | 100 µg/0.5 ml | $69.00 |