CCRF-HSB-2 Cell Lysate: sc-2265

The CCRF-HSB-2 Cell Lysate is derived from the CCRF-HSB-2 cell line, which consists of human T lymphocytes originally isolated from a patient with acute lymphoblastic leukemia of the T-cell type. This lysate is an aggregation of various cellular components, such as proteins, RNA, DNA, and lipids, extracted using methods including detergent lysis, ultrasonication, or enzymatic digestion. The origin of this cell line in a T-cell leukemia context provides a unique platform for researchers to study T-cell biology and the underlying mechanisms of cellular proliferation and signaling in a non-medical research environment. The CCRF-HSB-2 Cell Lysate is frequently employed in the study of cellular communication, signaling pathways, and the molecular machinery involved in cell cycle regulation and immune response modulation. This lysate aids in the exploration of protein expression, post-translational modifications, and interactions that are crucial for understanding the cellular dynamics and regulatory networks within T lymphocytes. By providing a detailed molecular snapshot of these cells, the CCRF-HSB-2 Cell Lysate enables research that helps delineate the complex biological processes that govern immune cell behavior, supporting broader research objectives that aim to explain fundamental cellular functions and mechanisms. This contributes substantially to advancing knowledge in cell biology and immunology, offering insights into the sophisticated orchestration of cellular activities.

CCRF-HSB-2 Cell Lysate References:

1. Stem cell factor and c-kit are expressed by and may affect vascular SMCs through an autocrine pathway.  |  Hollenbeck, ST., et al. 2004. J Surg Res. 120: 288-94. PMID: 15234225