Molecular structure of CBIQ, CAS Number: 32081-28-0
CBIQ (CAS 32081-28-0)
Alternate Names:
4-Chlorobenzo[f]isoquinoline
Application:
CBIQ is an activator of the cystic fibrosis transmembrane conductance regulator
CAS Number:
32081-28-0
Purity:
>95%
Molecular Weight:
213.66
Molecular Formula:
C13H8NCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
CBIQ is an aromatic compound that is created synthetically and possesses favorable properties such as stability and reactivity. As a starting material, CBIQ plays a pivotal role in the synthesis of various organic compounds. Furthermore, it serves as a catalyst in multiple reactions, including the synthesis of polymers and polyesters. While the precise mechanism of action of CBIQ is not yet fully comprehended, this compound is known to engage with various enzymes, including cytochrome P450 enzymes and cyclooxygenase-2.
CBIQ (CAS 32081-28-0) References
- Novel genes affecting urease acivity in Actinobacillus pleuropneumoniae. | Bossé, JT., et al. 2001. J Bacteriol. 183: 1242-7. PMID: 11157936
- 4-Chloro-benzo[F]isoquinoline (CBIQ) activates CFTR chloride channels and KCNN4 potassium channels in Calu-3 human airway epithelial cells. | Szkotak, AJ., et al. 2004. Br J Pharmacol. 142: 531-42. PMID: 15148241
- 4-Chlorobenzo[F]isoquinoline (CBIQ), a novel activator of CFTR and DeltaF508 CFTR. | Murthy, M., et al. 2005. Eur J Pharmacol. 516: 118-24. PMID: 15921678
- Structure and mechanism of a group-I cobalt energy coupling factor transporter. | Bao, Z., et al. 2017. Cell Res. 27: 675-687. PMID: 28322252
- Heat, cold, acid, and bile salt induced differential proteomic responses of a novel potential probiotic Lactococcus garvieae C47 isolated from camel milk. | Baig, MA., et al. 2022. Food Chem. 397: 133774. PMID: 35905615
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CBIQ, 5 mg | sc-252550 | 5 mg | $123.00 |