Molecular structure of CB-86, CAS Number: 1150586-64-3
CB-86 (CAS 1150586-64-3)
CAS Number:
1150586-64-3
Molecular Weight:
417.6
Molecular Formula:
C26H43NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
CB-86 is a resorcinol-anandamide hybrid compound that acts as a partial agonist for the central cannabinoid (CB1) receptor and a neutral antagonist for the peripheral cannabinoid (CB2) receptor with Ki values of 5.6 and 7.9 nM, respectively. Its demonstrated potency is similar to that of WIN 55,212-2 (Ki = 21 and 2. nM for CB1 and CB2, respectively). CB-86 (1 mg/kg) exhibits antinociceptive effects in mice treated with formalin.
CB-86 (CAS 1150586-64-3) References
- New resorcinol-anandamide 'hybrids' as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo. | Brizzi, A., et al. 2009. J Med Chem. 52: 2506-14. PMID: 19331413
- Retrospective analysis of synthetic cannabinoids in serum samples--epidemiology and consumption patterns. | Jaenicke, NJ., et al. 2014. Forensic Sci Int. 242: 81-87. PMID: 25050839
- Emerging Synthetic Cannabinoids: Development and Validation of a Novel Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry Assay for Real-Time Detection. | Krotulski, AJ., et al. 2020. J Anal Toxicol. 44: 207-217. PMID: 31909808
- Natural anti-inflammatory terpenoids in Camellia japonica leaf and probable biosynthesis pathways of the metabolome | Majumder, S., Ghosh, A., & Bhattacharya, M. 2020. Bulletin of the National Research Centre. 44: 1-14.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CB-86, 1 mg | sc-293987 | 1 mg | $37.00 | |||
CB-86, 5 mg | sc-293987A | 5 mg | $168.00 |